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The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The study found that sweat glands contain different types of stem cells that help with healing and maintaining healthy skin.

Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.

Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.

Androgens can both increase and decrease hair growth in different parts of the body.

Laser hair removal is the most requested cosmetic procedure and has become a scientifically-based treatment suitable for all skin types.

Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

A new microneedle patch made from hair proteins helps regrow hair faster and better than current treatments.

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Regenerated fully functional hair follicles using stem cells, with potential for hair regrowth therapy.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

Stem cell niches support, regulate, and coordinate stem cell functions.

Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.

HairMax LaserComb® effectively promotes hair growth and stops hair loss in males with androgenetic alopecia, with no serious side effects.

Stress-related substance P may lead to hair loss and negatively affect hair growth.