Skin stem cells in hair follicles are important for touch sensation.
12 citations,
January 2021 in “Cell Transplantation” Baby teeth stem cells can help grow hair in mice.
150 citations,
December 2012 in “EMBO Reports” Stem cell self-renewal is complex and needs more research for full understanding.
11 citations,
October 2021 in “Stem Cell Research & Therapy” Hair follicle stem cells reduced hair loss and inflammation in mice with a condition similar to human alopecia.
40 citations,
June 2011 in “Journal of biological chemistry/The Journal of biological chemistry” FA2H is essential for normal fur and sebum production in mice.
30 citations,
June 2014 in “Seminars in Immunology” Future research on ectodysplasin should explore its role in diseases, stem cells, and evolution, and continue developing treatments for genetic disorders like hypohidrotic ectodermal dysplasia.
72 citations,
July 2012 in “Journal of Investigative Dermatology” Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.
24 citations,
March 2018 in “Pigment Cell & Melanoma Research” The environment around melanocyte stem cells is key for hair regeneration and color, with certain injuries affecting hair color and potential treatments for pigmentation disorders.
14 citations,
December 2010 in “Dermatologica Sinica” New treatments for hair loss show promise, but more development is needed, especially for tough cases.
6 citations,
January 2017 in “Advances in Experimental Medicine and Biology” Runx genes are important for stem cell regulation and their roles in aging and disease need more research.
11 citations,
June 2016 in “npj Regenerative Medicine” The symposium concluded that understanding how different species repair tissue and how this changes with age can help advance regenerative medicine.
254 citations,
January 2012 in “Nature Reviews Molecular Cell Biology” Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.
February 2016 in “Online journal of biological sciences” Henna and honey improved burn healing and hair growth in rabbits.
68 citations,
May 2018 in “PLOS Biology” Cyclosporine A may help treat hair loss by blocking a protein that inhibits hair growth.
1 citations,
July 2014 in “International Journal of Dermatology” A cancer patient developed a type of hair loss after starting a cancer drug called vandetanib.
4 citations,
January 2015 in “International Journal of Trichology” Transplanted hair follicles can change and adapt to new areas of the body, with the immune system possibly playing a role in this adjustment.
67 citations,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Chronic Telogen Effluvium may resolve after years and is diagnosed by examining the patient's history and clinical signs, with treatment aimed at underlying causes and possibly minoxidil.
37 citations,
April 2011 in “Journal of Biological Chemistry” LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.
22 citations,
December 2015 in “The journal of investigative dermatology/Journal of investigative dermatology” A mouse gene mutation increases the risk of skin cancer.
43 citations,
December 2013 in “Seminars in Cell & Developmental Biology” Genetic mutations can cause hair growth disorders by affecting key genes and signaling pathways.
23 citations,
June 2010 in “Journal of Investigative Dermatology” A mutation in the Soat1 gene causes hair structure defects and other health issues in AKR/J mice.
42 citations,
March 2018 in “PLOS Biology” Autophagy is important for human hair growth and health.
19 citations,
November 2018 in “Nutrients” Annurca apple extract may protect mouse hair from damage by chemotherapy and could help treat hair loss without promoting cancer growth.
60 citations,
September 2015 in “Expert Review of Clinical Immunology” Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.
24 citations,
August 2011 in “Experimental Dermatology” The flap assay grows the most natural hair but takes the longest, the chamber assay is hard work but gives dense, normal hair, and the patch assay is quick but creates poorly oriented hair with some issues.
4 citations,
May 2019 in “Skin Research and Technology” Finasteride helps hair growth but stopping it causes faster hair loss.
291 citations,
April 2010 in “Gastroenterology” Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.
286 citations,
August 2007 in “Journal of Clinical Investigation” Alopecia areata is an autoimmune disease where T cells attack hair follicles.
11 citations,
February 2019 in “Journal of Cosmetic Dermatology” Low zinc and biotin levels linked to male hair loss; supplements may help.
81 citations,
September 2009 in “Birth defects research” Different body areas in mice produce different hair types due to interactions between skin layers.