The Genetics of Alopecia Areata

December 2001 in “ Dermatologic Therapy ”

Vincent M. Aita, Angela M. Christiano

alopecia areata genetics HLA alleles microarray analyses SNPs Human Genome Project

Studysummary This review summarizes current genetic knowledge of alopecia areata and provides a theoretical framework for future genetic mapping studies, but reports no new results.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

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research Role of Cytotoxic T Cells in Chronic Alopecia Areata

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This study found that pro-inflammatory cytokines and apoptotic mechanisms, specifically involving granzyme B and Fas pathways, are associated with chronic alopecia areata, indicating their potential role in the disease's persistence.

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This study identified a missense mutation in the human hairless gene associated with a rare form of recessively inherited alopecia universalis, pinpointed on chromosome 8p12.

research The Inheritance Of Common Baldness: To Be Or Not To Be?

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This study presents evidence suggesting that androgenetic alopecia is most likely inherited through a polygenic model, challenging the traditional view that it is caused by a simple Mendelian autosomal dominant gene.

research Immunohistochemical and Electron Microscopic Characterization of the Cellular Infiltrate in Alopecia Areata, Totalis, and Universalis

78 citations , July 1984 in “Journal of Investigative Dermatology”