September 2022 in “Biomedicines” This study found that lipid accumulation product (LAP) and free androgen index (FAI) can highly predict liver steatosis in women with PCOS phenotype A.
6 citations
,
January 2017 in “British Journal of Dermatology” This article reviews frontal fibrosing alopecia, exploring its characteristics, demographics, and associated conditions, and calls for controlled trials due to an increase in worldwide cases; it reports no new findings.
2 citations
,
January 2023 in “Uro” This study found that both a proprietary ultrahigh-pressure extract and a hexanic extract of saw palmetto showed comparable inhibition of 5α-reductase, suggesting similar potential for managing symptoms of benign prostatic hyperplasia.
11 citations
,
June 2010 in “Medical Molecular Morphology”
39 citations
,
August 2004 in “International journal of gynaecology and obstetrics” This study found that both finasteride and a regimen of cyproterone acetate plus ethinyl estradiol effectively reduced hirsutism in women, with similar results despite differing hormonal effects.
August 2023 in “Cell Proliferation” This study observed that incorporating human follicle dermal papilla cells into fibrin microgels increased cell viability and the formation of hair follicle structures in in vitro skin cultures compared to traditional dermal papilla spheroids, suggesting a promising approach for hair follicle regeneration therapies.
6 citations
,
August 2014 in “Sri Lanka Journal of Diabetes Endocrinology and Metabolism” This study concluded that the modified Ferriman-Gallwey score was more effective in detecting hyperandrogenism in PCOS patients compared to serum testosterone and free androgen index in Sri Lankan women.
22 citations
,
January 2019 in “Endocrinology and metabolism” This study found that among Filipino women, a modified Ferriman-Gallwey score of 7 or above indicates hirsutism and is significantly associated with elevated calculated free testosterone.
24 citations
,
November 2013 in “Molecular Medicine Reports” This study demonstrated that human hair follicle stem cells can be efficiently differentiated into endothelial-like cells using VEGF and bFGF, suggesting their potential as a novel cell source for vascular tissue engineering.
55 citations
,
June 2007 in “Journal of Statistical Planning and Inference” This study introduces an extended approach to the Bonferroni procedure that accounts for correlations among endpoints, aiming to improve test power while maintaining strong control of the family-wise type I error rate in clinical trials.
71 citations
,
October 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” This study presents a novel in vitro assay using human folliculoid microspheres to research hair growth, which may facilitate preclinical testing of hair growth-modulatory agents.
January 2026 in “Medicine” This study suggests that Hejie Shengfa Decoction may help treat alopecia areata by influencing immune and inflammatory pathways, regulating apoptosis, and enhancing the follicular microenvironment.
August 2026 in “ACTA MEDICA IRANICA” This study found that women with female pattern hair loss exhibited hormonal imbalances, with the Free Androgen Index being a particularly effective diagnostic marker.
February 2018 in “Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano)” This study concluded that macrophage iron retention due to Ferroportin inactivation hinders skin wound healing but does not affect liver damage or fibrogenesis in a mouse model.
2 citations
,
September 2023 in “Frontiers in molecular biosciences” This review highlights the potential of targeting hepatic stellate cell ferroptosis as a treatment strategy for liver fibrosis, underscoring the need for further research into ferroptosis mechanisms in these cells to better understand and combat this condition.
May 2012 in “F1000Research” This research consisted of a Phase I/II study on androgenetic alopecia where male participants received intradermal injections of HSC, with hair growth efficacy assessed through Trichoscan imaging, although no new clinical results are reported.
23 citations
,
February 2014 in “Journal of Pediatric and Adolescent Gynecology” This study found that a low-dose intermittent finasteride regimen significantly reduced hirsutism scores in adolescent girls with PCOS or idiopathic hirsutism, with similar efficacy but potentially safer and less expensive than continuous administration.
40 citations
,
January 2010 in “Annales D Endocrinologie” This article discusses diagnostic guidelines for PCOS, emphasizing the use of the Rotterdam criteria and recommending clomiphene citrate as the first-line treatment for ovulation induction; it reports no new clinical results.
8 citations
,
February 2010 in “Journal für Kardiologie (Krause & Pachernegg GmbH)” This study developed a detailed classification system for functional androgenization in females that may enhance diagnosis and personalized treatment by identifying individual dysfunctions.
September 2023 in “Pharmaceutics” In this study, the authors developed a medicated face mask using electrospun fibers to deliver the active compound Eflornithine hydrochloride for managing hirsutism. The mask showed promising drug release characteristics, a high safety profile, and reduced hair growth in mice.
16 citations
,
April 2018 in “Current opinion in gynecology and obstetrics” The study observed that Hispanic women with PCOS had significantly higher odds of having NASH compared to non-Hispanic women, suggesting routine screening may be beneficial in this high-risk group.
August 2026 in “Transplantation and Cellular Therapy” This study found that serum-free expanded hair follicle mesenchymal stem cells (hfMSCs), derived from hair plucking, significantly improved cartilage repair in a murine model despite minimal engraftment, suggesting their effectiveness through a paracrine mechanism.
64 citations
,
January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that ectodermal precursor cells derived from human induced pluripotent stem cells may enhance hair follicle morphogenesis through improved epithelial-mesenchymal interactions when cocultured with dermal cells.
2 citations
,
September 2024 in “Pharmaceuticals” This study suggests that human placenta hydrolysate reduces CFA-induced inflammatory pain in mice by inhibiting pro-inflammatory cytokines and protecting peripheral nerves.
75 citations
,
October 1999 in “European journal of endocrinology” This study found that both finasteride and flutamide effectively reduce hirsutism in women with polycystic ovary syndrome or idiopathic hirsutism, but flutamide was more effective.
1 citations
,
August 2020 in “Research Square (Research Square)” This study found that hair follicle stem cell transplantation in a rat model of ischaemic stroke reduced infarct volume and promoted neurological recovery, suggesting potential therapeutic benefits for stroke treatment.
June 2016 in “The Egyptian Journal of Fertility and Sterility” This review discusses strategies for managing hirsutism in PCOS, highlighting lifestyle changes, hormonal treatments, and the importance of patient-centered care, but reports no new clinical results.
1 citations
,
January 2009 in “PubMed” This systematic review evaluates the effectiveness and safety of various treatments for polycystic ovary syndrome including finasteride, flutamide, and metformin, but does not provide specific new results.
1 citations
,
January 2008 in “Springer eBooks” This study found that hair follicle stem cells are multipotent and can enhance nerve regeneration and function in mice, showing potential as an accessible source for treating peripheral nerve injuries.
January 2025 in “Biochemical Pharmacology” In this study, fibroblasts treated with the small molecule peficitinib were reprogrammed into dermal papilla cell-like cells capable of inducing hair growth, offering a new strategy for hair loss treatment.