TLDR The study concluded that personalized treatment, including medical and cosmetic approaches, is effective for women with PCOS and hirsutism.
The 2016 study by Ahmed Aboul Serour focused on Polycystic Ovarian Syndrome (PCOS), which affected 5-15% of women and was the most common cause of hirsutism, with a prevalence of 70-80% in PCOS patients compared to 4%-11% in the general female population. The study highlighted that there was no universal agreement on the definition of PCOS, with different organizations using varying criteria. The research also found that hirsutism in PCOS was due to excess production of ovarian androgen driven by high levels of LH. Lifestyle modifications and weight loss were recommended for PCOS patients with hirsutism. Medical treatments such as combined hormonal contraceptives (CHCs), antiandrogens, or a combination of both, as well as insulin sensitizers were found to be effective, especially when associated with hyperinsulinemia. The study concluded that the management strategy for PCOS patients with hirsutism should be patient-centered, and both medical and cosmetic treatments were effective.
Cited in this study
5 / 5 results
89 citations
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January 2015 in “Medical Clinics of North America” Eating 500 fewer calories a day and making lifestyle changes can improve PCOS symptoms and reduce diabetes risk; more research is needed on its causes and treatments.
150 citations
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April 2008 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Antiandrogens are somewhat effective in reducing excessive hair growth in women.
75 citations
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November 2007 in “Clinical endocrinology” Certain medications including flutamide, spironolactone, and others effectively reduce excessive hair growth in women, especially when combined with lifestyle changes.
947 citations
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February 2004 in “The Journal of Clinical Endocrinology and Metabolism” Most women with excess male hormones have Polycystic Ovary Syndrome, and hormonal therapy can improve symptoms but may cause side effects.
57 citations
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January 1995 in “The American journal of medicine” Oral contraceptives help treat hyperandrogenic disorders, improving symptoms like excessive hair and acne.
19 citations
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April 2018 in “JAMA” Treat hirsutism in premenopausal women with oral contraceptives and consider additional treatments if needed.
54 citations
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August 2017 in “Gynecological Endocrinology” Lifestyle changes and weight loss are key for treating PCOS-related metabolic issues and infertility, with various medications available for specific symptoms.
47 citations
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November 2016 in “Current pharmaceutical design” The document concludes that managing hirsutism in PCOS involves long-term treatment guided by severity, using oral contraceptives and possibly antiandrogens, with attention to individual patient needs.
22 citations
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September 2011 in “Endocrine Practice” Most hirsutism cases are due to PCOS, and treatment focuses on lowering testosterone and blocking its effects.
12 citations
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October 2004 in “Expert Opinion on Investigational Drugs” Treatments for Polycystic Ovary Syndrome (PCOS) focus on reducing symptoms, restoring regular periods, and helping with pregnancy. Common treatments include hormone suppressors, fertility drugs, and insulin-sensitising agents.