Evaluation and Treatment of Hirsutism in Premenopausal Women

    March 2018 in “ JAMA ”
    Mizuho S. Mimoto, Julie Oyler, Andrew M. Davis
    TLDR Treat hirsutism in premenopausal women with oral contraceptives and consider additional treatments if needed.
    The guideline for evaluating and treating hirsutism in premenopausal women, developed by the Endocrine Society and other related organizations, recommended obtaining a random serum total testosterone measurement for women with abnormal hirsutism scores to assess androgen excess. For those with elevated testosterone or at high risk of congenital adrenal hyperplasia, an early-morning 17-hydroxyprogesterone measurement was advised. Pharmacologic treatment should start with oral contraceptive pills (OCPs) for women not seeking pregnancy, with the addition of direct hair removal methods if necessary. Combination therapy with an antiandrogen was suggested if significant hirsutism persisted after 6 months of OCP monotherapy. All recommendations were based on weak and low-quality evidence.
    Discuss this study in the Community →

    Research cited in this study

    2 / 2 results

    Related Community Posts Join

    6 / 24 results

      community How does hair loss and recovery work?

      in Chat  12 upvotes 2 months ago
      Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.

      community Methionine? Glycine?

       6 upvotes 8 years ago
      The conversation discusses the potential benefits and risks of using Methionine and Glycine for hair loss, with concerns about cancer risk if not balanced properly. The user seeks opinions on these amino acids for hair health and overall benefits.

      community Spironolactone for 11 years, finasteride for almost 5 years, started oral minoxidil in November 😢 ended oral contraceptive in Dec.

      in Progress Pictures  224 upvotes 7 months ago
      A user shared their 11-year experience with spironolactone and nearly 5 years with finasteride for hair loss, recently adding oral minoxidil and stopping birth control. Various treatments were discussed, including organic options, checking for underlying health issues, considering dutasteride, and the potential role of progesterone in hair loss.

      community DHT levels after 4 weeks of Fina and 8 weeks of Fina + 4 weeks of Duta

      in Update  36 upvotes 5 years ago
      The user reported early stage diffuse hair thinning and increased DHT levels after 4 weeks on Finasteride and 8 weeks on Finasteride plus 4 weeks on Dutasteride, despite the medications being authentic and stored properly. They are considering increasing their Dutasteride dosage due to the lack of side effects and are unsure if the treatment is helping their hair.

      community Opinions on Scalp fibrosis and DHT?

      in Research/Science  9 upvotes 2 years ago
      The conversation discusses the theory that scalp fibrosis contributes to male pattern baldness (MPB) by increasing DHT concentration, and mentions treatments like Minoxidil. The user seeks opinions on the theory and the effectiveness of scalp massages.

      community Does low HGH leading to hairloss?

      in Research/Science  13 upvotes 9 months ago
      The user experiencing diffuse hair loss is using various treatments including RU58841, finasteride, minoxidil with tretinoin, anti-hair loss shampoo, and microneedling, and is considering adding peptides TB500, BPC157, and GHK-Cu. They have low growth hormone levels and are questioning its impact on hair loss, while another user suggests androgenic alopecia and androgens are likely the main cause of hair loss.

    Similar Research

    6 / 1000+ results