Recent Advances in the Treatment of Polycystic Ovary Syndrome
October 2004
in “
Expert Opinion on Investigational Drugs
”
polycystic ovary syndrome PCOS hyperandrogenism hirsutism androgen suppressors peripheral androgen blockers combined oral contraceptive pills menstrual dysfunction clomiphene-citrate parenteral gonadotropins insulin-sensitising agents metabolic disturbances birth control pills clomid gonadotropins insulin sensitizers
TLDR Treatments for Polycystic Ovary Syndrome (PCOS) focus on reducing symptoms, restoring regular periods, and helping with pregnancy. Common treatments include hormone suppressors, fertility drugs, and insulin-sensitising agents.
The document from 2004 discusses the treatment strategies for Polycystic Ovary Syndrome (PCOS), a common endocrine disorder in reproductive-aged women. The treatment was primarily targeted to the patient's primary complaint, focusing on reducing hyperandrogenism symptoms, restoring regular menses, and achieving pregnancy. Pharmacological agents for hirsutism treatment included androgen suppressors and peripheral androgen blockers. Combined oral contraceptive pills were the most commonly used androgen suppressor and the treatment of choice for menstrual dysfunction in PCOS patients not desiring pregnancy. The first-line treatment for infertility in PCOS was clomiphene-citrate, while parenteral gonadotropins were used in clomiphene-resistant patients. The benefits of insulin-sensitising agents for PCOS patients had become increasingly clear over the last decade. Metabolic disturbances associated with PCOS appeared to have important long-term health implications and required further attention.
