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Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Pregnancy can cause specific skin conditions that need correct diagnosis and treatment to protect both mother and baby.

Finasteride reduces new brain cells in male mice, possibly causing depression.

17-β-Estradiol applied to the skin stops hair growth, while ICI 182 780 helps hair grow in mice.

Menopause affects hair and skin; more research needed for treatment.

Late pregnancy helps repair brain damage in rats due to the GABAergic system.

Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.

Insulin resistance in women with PCOS can lead to serious health issues, but lifestyle changes and certain medications can help manage symptoms.

Subcutaneous contraceptives can cause side effects like menstrual changes, headaches, weight gain, and pain at the implant site.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

The document says that understanding the causes of PCOS is important for treatment, especially in distinguishing the syndrome from just having cystic ovaries, and that losing weight is key for obese women with PCOS.

Post-finasteride syndrome causes lasting sexual, neurological, and physical side effects in some people after taking finasteride.

Hormonal treatments can improve acne, but they come with potential side effects and risks.

Finasteride affects prostate weights and pituitary activity differently with age.

Taking spironolactone and linestrenol for androgen excess can lead to lower bone density in young women.

Mutations in certain receptors can cause diseases and offer new treatment options.

Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.

Most pregnant women experience skin changes like darkening and itching, while serious skin conditions are rare but need early treatment.

Different anti-androgen medications can help treat excessive hair growth, but the right choice depends on accurate diagnosis.

Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.

Male rats have androgen receptors in their liver, which are different from proteins that bind estrogen.

Minoxidil promotes hair regrowth, but more research needed for effectiveness and response factors.

Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.

New male hormonal contraceptives show promise but need more research on long-term effects and funding for larger trials.

Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.

Birth control pills help treat skin and hair growth problems linked to high male hormone levels.

Newer low-dose oral contraceptives with less androgenic effects improve patient compliance.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Women with PCOS, especially those overweight, have higher levels of IL-18 in their endometrium, which may affect fertility.

Higher hs-CRP levels in Indian adolescent women with PCOS are more related to BMI than PCOS itself.