Dihydrotestosterone Stimulates 5α-Reductase Activity in Pubic Skin Fibroblasts
February 1983
in “
The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism
”
dihydrotestosterone 5α-reductase testosterone androgen receptor cyproterone acetate estradiol cortisol protein synthesis pubic skin fibroblasts testicular feminization syndrome DHT 5-alpha reductase T androgen receptor cyproterone acetate estradiol cortisol protein synthesis PSF testicular feminization syndrome
Studysummary This study found that pubic skin fibroblasts respond to androgens, increasing 5α-reductase activity via an androgen receptor-mediated mechanism, suggesting its potential as a marker of androgen action in vitro.
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