Origin, Clinical Presentation, and Diagnosis of Facial Hypermelanoses

    July 2007 in “ Dermatologic clinics ”
    Electra Nicolaidou, Christina Antoniou, Andreas Katsambas
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    TLDR Facial dark spots can be caused by the sun, genetics, makeup, or medicine, and are diagnosed by patient history and skin tests.
    In 2007, it was understood that facial hypermelanosis, which includes conditions like melasma, can be caused by various factors such as sun exposure, genetics, cosmetics, and certain medications. To diagnose these disorders, a thorough personal and family history along with histopathologic examination were typically sufficient. Additionally, systemic conditions like Addison's disease were considered important to rule out when diagnosing facial hypermelanoses.
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