Activity of Isoflavone in Managing Polycystic Ovary Syndrome Symptoms: A Review

March 2024 in “ Biomedical reports ”

Cut Raihanah, Sukrasno Sukrasno, Neng Fisheri Kurniati

isoflavone phytoestrogen testosterone menstrual cycles ovarian morphology metabolic profile inflammatory markers oxidative stress polycystic ovary syndrome PCOS

Studysummary This review discusses existing literature on the effects of isoflavone in alleviating PCOS symptoms, highlighting its potential benefits in reducing testosterone levels, improving metabolic profiles, and lowering inflammation and oxidative stress, although findings have been both significant and non-significant. Our plain-language summary of this paper — not a Tressless recommendation.

Isoflavone, a phytoestrogen, shows potential in managing polycystic ovary syndrome (PCOS) symptoms by lowering testosterone levels, normalizing menstrual cycles, and improving ovarian morphology. It also positively affects the metabolic profile and reduces inflammatory markers and oxidative stress. However, the results on its efficacy are mixed, with both significant and non-significant outcomes reported. This review discusses the existing literature on isoflavone's effects on PCOS symptoms based on in vivo and clinical trial studies.

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