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June 1995 in “The American Journal of the Medical Sciences” Finasteride caused enlarged breast tissue in a 62-year-old man.
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September 2018 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” A boy's growth and immune problems were caused by a new mutation in the STAT5B gene.
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October 2010 in “Seizure” Extended-release valproate effectively reduced seizures and improved quality of life in epilepsy patients over 6 months, with some side effects.
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October 2002 in “Journal of Biochemical and Biophysical Methods” Men with male-pattern baldness have higher levels of certain testosterone metabolites and may have more active androgen metabolism.
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September 2019 in “Scientific Reports” High levels of the protein Flightless I worsen ulcerative colitis symptoms in mice.
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January 2019 in “Skin Research and Technology” Southern Chinese women with female pattern hair loss have less, thinner hair and smaller hair follicles.
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September 2015 in “Reproductive Biomedicine Online” Longer GGN repeats in the androgen receptor gene are linked to polycystic ovary syndrome.
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November 2003 in “Current Opinion in Obstetrics & Gynecology” Metformin helps improve symptoms and reproductive outcomes in people with polycystic ovary syndrome.
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February 2021 in “Legal Medicine” Hair analysis showed very high metformin levels in two fatal overdose cases, suggesting it's useful in forensics but sweat may affect results.
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September 2020 in “Journal of Cosmetic Dermatology” Minoxidil and Finasteride are the most popular hair loss treatments, with rising interest in other options, and economic or health crises can change what treatments people prefer.
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March 2021 in “International Journal of Pharmaceutics” Optimal long-acting finasteride injection dose found: 16.8 mg, effective for one month.
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September 2020 in “Andrologia” Oregano extract helps fix testis and sperm damage caused by finasteride.
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April 2016 in “Journal of Dermatology Research and Therapy” Anti-androgens are safe and effective for treating moderate to severe adult female acne.
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March 2014 in “The FASEB Journal” The HIF-2α/ARNT complex is important for hair follicle development by controlling cell growth.
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January 2012 in “Elsevier eBooks” The document concludes that various skin conditions have specific treatments, ranging from antihistamines for urticaria to surgery and medication for tumors and chronic skin diseases.