February 2025 in “Folia Medica” This study found that men with androgenetic alopecia had significantly lower serum vitamin D levels compared to controls and the deficiency strongly correlated with the severity of the condition.
August 2016 in “Annals of International medical and Dental Research” This study found that patients with alopecia had significantly higher mean serum ferritin levels compared to controls, except for those with telogen effluvium, whose levels were not significantly different.
28 citations
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April 2017 in “Journal of cosmetic dermatology” This study found that while vitamin D deficiency is not the sole cause of alopecia areata, it may worsen the disease, suggesting supplementation could help in pediatric cases.
8 citations
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July 2022 in “Metabolites” This study found that among middle-aged Korean men, higher serum uric acid levels were associated with a reduced risk of developing lower urinary tract symptoms.
5 citations
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May 2018 in “Journal of the American Academy of Dermatology” This study found no significant correlation between vitamin D levels and disease severity in alopecia areata patients, highlighting the need for further research on vitamin D supplementation's effects.
April 2025 in “Egyptian Journal of Medical Research” This study found that individuals with Telogen Effluvium had significantly lower levels of vitamin D compared to healthy individuals, with a particularly negative correlation observed between disease duration and vitamin D levels in affected patients.
January 2025 in “Indian Journal of Paediatric Dermatology” This study found no significant difference in serum Vitamin D levels between children with alopecia areata and healthy controls, nor was there any correlation between Vitamin D levels and the severity, duration, or pattern of the condition, or nail changes.
January 2025 in “International Journal of Gynaecology Research” This study found that serum cystatin C levels may be elevated in adolescent females with PCOS, suggesting it could serve as a predictive marker for metabolic and cardiovascular issues independent of renal function.
December 2020 in “Our Dermatology Online” This study found that there was a significant discrepancy between histopathological examination and clinical diagnosis in alopecia cases, while vitamin D levels were not significantly associated with alopecia.
January 2014 in “Dongwu yingyang xuebao” The study concluded that a dietary vitamin A level of 10,000 IU/kg optimally supports growth performance, fur quality, and antioxidant function in growing Rex rabbits.
August 2026 in “Glosains Jurnal Sains Global Indonesia” In this cross-sectional study of Indonesian men, researchers observed a significant negative correlation between serum vitamin D levels and the severity of androgenetic alopecia, suggesting that lower vitamin D concentrations are associated with more severe hair loss, although causality was not established.
August 2025 in “International Journal of Science and Research (IJSR)” This study, conducted at a tertiary care center in India, found a high prevalence of vitamin D deficiency and insufficiency among patients with alopecia areata, though no statistically significant correlation between vitamin D levels and disease severity or duration was observed.
May 2023 in “Minia Journal of Medical Research” This study assessed vitamin D levels in both serum and hair among 80 male and female participants from a dermatology clinic and found no significant gender-related differences in these vitamin D levels.
May 2023 in “GLOBAL JOURNAL FOR RESEARCH ANALYSIS” This study found that males with early onset androgenetic alopecia had significantly lower serum vitamin D levels compared to age-matched healthy controls, although no correlation between the severity of alopecia and vitamin D levels was observed.
This study found that young adults, particularly females, experiencing diffuse hair fall had significantly lower Vitamin D3 levels compared to their age-matched healthy counterparts.
14 citations
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January 2013 in “Journal of the Egyptian Women's Dermatologic Society /Journal of the Egyptian Women's Dermatologic Society” 7 citations
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October 2011 in “Faṣlnāmah-i bīmārīhā-yi pūst” This study found that serum iron and ferritin levels in patients with alopecia areata did not significantly differ from control subjects, suggesting these factors may not contribute to the condition's etiology.
May 2026 in “Electronic Journal of General Medicine” In this study, researchers found that women with PCOS and insulin resistance had higher irisin levels, while both PCOS groups had lower betatrophin levels compared to controls. These distinct biomarker alterations could aid in better metabolic profiling and risk assessment for PCOS.
19 citations
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October 2019 in “BMC Neuroscience” This study found weak to very weak correlations between estradiol, progesterone, and testosterone levels in the cerebrospinal fluid and serum of males without cerebral disorders.
2 citations
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September 2021 In this study, serum 25-hydroxyvitamin D levels were similar between alopecia areata patients and healthy controls, though a non-significant trend toward higher vitamin D deficiency was observed among the patients.
December 2025 in “Frontiers in Endocrinology” This study found that elevated CgA levels in PCOS are associated with obesity, insulin resistance, and low-grade inflammation, suggesting CgA may be a novel biomarker for metabolic risk stratification in PCOS.
January 2025 in “Egyptian Journal of Dermatology and Venerology” This study found that COVID-19 vaccination initially lowered vitamin D levels in serum and hair but increased serum levels after the second dose, except for the Pfizer group. Hair vitamin D showed a nonsignificant increase, and hair loss was most common with the AstraZeneca vaccine.
January 2025 in “Mansoura Medical Journal” This study examined serum ischemia-modified albumin levels in men with androgenic alopecia compared to healthy controls and found no diagnostic value, though higher levels were associated with more severe alopecia, indicating potential involvement in disease progression.
June 2024 in “Benha Journal of Applied Sciences” This study suggests that ischemia-modified albumin may play a role in premature hair graying and vasogenic erectile dysfunction, potentially serving as indicators of susceptibility and severity.
September 2023 in “Diagnostics” In this study, researchers found a significant relationship between mid-luteal progesterone levels and 25-hydroxy vitamin D levels in infertile patients, suggesting that about 20 ng/mL of vitamin D may be necessary to trigger ovulation or support progesterone secretion.
September 2023 in “Clinical, Cosmetic and Investigational Dermatology” This study found a significant negative correlation between serum SHBG levels and androgenetic alopecia severity in women, but not in men, while no significant correlation was observed for testosterone, estradiol, dehydroepiandrosterone sulfate, and vitamin D levels with hair loss severity across genders.
May 2021 in “Indian journal of forensic medicine and toxicology” This study found that adult female patients with chronic telogen effluvium had significantly lower serum ferritin and vitamin D levels compared to healthy controls, suggesting a potential association with hair loss.
September 2019 in “Human Andrology” This study showed that men with androgenetic alopecia had higher serum levels of testosterone and DHT compared to controls, but no difference in PSA levels.
November 1986 in “PubMed” In this study, women with male pattern alopecia had significantly lower serum sex hormone binding globulin levels compared to healthy controls, while testosterone levels remained similar.
83 citations
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April 1992 in “Clinical Endocrinology” This study found that treatment with cyproterone acetate and ethinyl oestradiol increased hair density in women with diffuse androgen-dependent alopecia, particularly when serum ferritin levels were above 40 μg/l.