Serum Uric Acid Level in Male Patients With Androgenetic Alopecia: A Prospective Study in China

The prospective study involved 120 male patients with androgenetic alopecia (AGA) and 120 males without AGA. The study found that the mean serum uric acid (UA) level in patients with AGA was higher than that in the control group (401.52±83.27 umol/L vs 362.67±60.88 umol/L). A higher proportion of hyperuricemia was also found in patients with AGA (29.17% vs 15.00%). After treatment with finasteride, the mean serum UA level in the AGA group decreased significantly, from 405.87±87.12 umol/L to 381.84±82.50 umol/L. Patients with AGA with hyperuricemia had a higher BMI (25.38±3.43 kg/m2) compared to those without hyperuricemia (23.88±2.64 kg/m2). For every unit of BMI increase in patients with AGA, the risk of hyperuricemia increased by 30.5%. The study concluded that AGA has a relationship with hyperuricemia, and the level of serum UA can decrease with the treatment of finasteride.