1 citations
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August 2024 in “Skin Research and Technology” This study found no significant causal relationship between androgenetic alopecia and serum uric acid levels using various Mendelian randomization methods, suggesting the need for future research with larger cohorts and advanced methods to further explore this potential association.
May 2024 in “Journal of cosmetic dermatology” This study found that early-onset male androgenetic alopecia is associated with abnormal lipid metabolism and lower levels of certain serum markers, which may serve as risk factors or protective factors for the condition.
February 2024 in “Heliyon” In this study, AGA patients exhibited distinct lipidomic profiles and higher metabolic syndrome prevalence compared to controls, with certain lipids correlated to key AGA-related factors like DHT, PGD2, and TGF-β1.
August 2023 in “Psychology, Health & Medicine” This systemic review and meta-analysis found that men with androgenetic alopecia generally experience moderate impacts on quality of life, but limited evidence of severe effects on mental health.
August 2023 in “The American Journal of the Medical Sciences” This study found that men with androgenetic alopecia had higher serum uric acid levels and a greater incidence of hyperuricemia compared to those without, but finasteride treatment significantly reduced uric acid levels over six months.
April 2023 in “Nigerian Journal of Clinical Practice” In this study, androgenetic alopecia in Nigerians was associated with dyslipidemia, alcohol intake, and sedentary lifestyle, with severity linked to age, systolic blood pressure, and obesity.
December 2022 in “Biomedicine” This study found that men with early onset androgenetic alopecia often have higher serum uric acid levels and an increased prevalence of hyperuricemia compared to controls.
November 2022 in “Frontiers in Medicine” This study found no direct association between androgenetic alopecia and metabolic syndrome in the Chinese population, though AGA was closely linked with higher systolic blood pressure in men.
September 2022 in “Dermatology and therapy” This review discusses the pathological factors and comorbidities associated with androgenetic alopecia and reports no new clinical results, emphasizing the need for improved understanding and treatment in clinical practice.
January 2021 in “Postepy Dermatologii I Alergologii” This study evaluated oxidative stress parameters in patients with androgenetic alopecia but does not report new clinical outcomes.
4 citations
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April 2020 in “Journal of Cosmetic Dermatology” This study found that men with early androgenetic alopecia have a higher prevalence of hyperuricemia compared to those without the condition.
30 citations
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December 2017 in “Medical Hypotheses” This review evaluates dihydrotestosterone's role in androgenic alopecia and proposes a model suggesting that chronic scalp tension and inflammation contribute to hair follicle miniaturization, identifying fibrosis, calcification, and tension as treatment targets.
153 citations
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March 2017 in “Endocrine” This review examines recent advances in understanding the pathophysiology and molecular mechanisms of androgenetic alopecia, highlighting two major genetic risk loci, but does not report new clinical findings.
93 citations
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February 2015 in “Journal of Investigative Dermatology” This study suggests that oxidative stress may contribute to androgenetic alopecia by inducing premature senescence and secretion of hair growth inhibitors in dermal papilla cells from balding scalp.
19 citations
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November 2010 in “PubMed” This review discusses advancements in the genetic understanding of androgenic alopecia and the FDA-approved treatments, including a new laser hair comb, but reports no clinical results.
55 citations
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June 2006 in “Central European Journal of Public Health” This study observed that Finnish men aged 63 with androgenetic alopecia had higher rates of hypertension and diabetes compared to those with normal hair status.
