Polymorphisms of the Genes ABCG2, SLC22A12, and XDH and Their Relation with Hyperuricemia and Hypercholesterolemia in Mexican Young Adults

    March 2021 in “ F1000Research ”
    Juan Manuel Vargas‐Morales, Martha Guevara‐Cruz, A. Celia, Lilia G. Noriega, Armando R. Tovar, Jorge Alejandro Alegría‐Torres
    TLDR A specific gene variation increases the risk of high uric acid and cholesterol in young Mexican males.
    This study investigated the relationship between genetic polymorphisms and hyperuricemia in 860 Mexican young adults aged 18-25. It found that the ABCG2 (rs2231142) polymorphism was significantly associated with an increased risk of hyperuricemia and hypercholesterolemia, particularly in males. Other factors linked to hyperuricemia included male sex, being overweight or obese, and having hypercholesterolemia or hypertriglyceridemia. The findings suggested that the ABCG2 polymorphism could be a genetic predisposition for these conditions in young Mexican males.
    Discuss this study in the Community →

    Research cited in this study

    2 / 2 results