Evaluation of Serum Level of Zinc Alpha 2 Glycoprotein in Male Patients with Androgenetic Alopecia

    December 2023 in “ Benha Journal of Applied Sciences
    Mohamed H. Bahnasawy, Asmaa Al Refaei, Mohamed Saber Hussein, walid Abdellatif
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    TLDR Men with male pattern baldness have higher blood sugar, bad cholesterol, and ZAG protein levels than healthy men.
    The research paper "Evaluation of Serum Level of Zinc Alpha 2 Glycoprotein in Male Patients with Androgenetic Alopecia" studied the blood levels of insulin resistance and Zinc Alpha 2 Glycoprotein (ZAG) in 60 male patients with Androgenetic Alopecia (AGA) compared to 20 healthy volunteers. The study found that AGA patients had significantly higher fasting glucose levels (84±12 mg/dl) compared to controls (78±6 mg/dl), with a p-value of 0.003. AGA patients also had significantly higher levels of LDL (106.2±25.6 mg/dl) compared to controls (95.9±10.1 mg/dl, P = 0.012). The median ZAG level in AGA patients was 12.1µg/ml, significantly higher than the control group's median level of 7.6µg/ml (P = 0.023). This suggests that ZAG could be a potential biomarker for AGA.
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