Assessment of Serum Levels of Antigliadin Antibodies (IgG and IgA) in Patients with Alopecia Areata and Their Relation to Severity of the Disease

    January 2022 in “ Al-Azhar Medical Journal ”
    Image of study
    TLDR Higher antigliadin antibody levels are linked to alopecia areata severity.
    This study evaluated serum levels of antigliadin antibodies (IgA and IgG) in 30 patients with alopecia areata (AA) compared to 30 healthy controls. Results showed that antigliadin IgA was positive in 26.7% of AA patients, while IgG was positive in all AA patients and 6.7% of controls. There was a significant difference in IgA and IgG levels between patients and controls, with higher values in patients. The study found 100% sensitivity and specificity for both IgA and IgG in diagnosing AA, suggesting a strong association between antigliadin antibodies and AA severity. The study recommends serological screening for celiac disease in AA patients.
    Discuss this study in the Community →

    Research cited in this study

    4 / 4 results

    Related Community Posts Join

    6 / 1000+ results

      community Alopecia Areata Question

      in Treatment  2 upvotes 3 years ago
      A user with alopecia totalis, borderline universalis, seeks advice on getting into a Xeljanz trial or appealing insurance for coverage. They experienced significant hair regrowth but are now seeing hair loss again and want to try Xeljanz.

      community mbp alopecia areata or vitamin deficiency

      in Chat 5 months ago
      A 19-year-old male has been using topical finasteride and minoxidil for 8 months with no progress and is considering seeking a second opinion due to potential misdiagnosis. The discussion revolves around whether the hair loss is due to male pattern baldness, alopecia areata, or a vitamin deficiency.

      community Olumiant alternative for Alopecia Areata?

      in Treatment  1 upvotes 1 year ago
      A user with alopecia areata is considering treatment options like injections or Olumiant but is concerned about cost and whether delaying treatment will lead to permanent hair loss. They are seeking alternative treatments that are more affordable for a college student.

    Similar Research

    5 / 1000+ results