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    Glossary Serine Protease

    enzyme that breaks down proteins by cleaving peptide bonds

    Serine proteases, also known as serine endopeptidases, are a group of enzymes that break down proteins by cleaving peptide bonds. They are named for the serine residue in their active site, which plays a crucial role in the catalytic process. These enzymes are involved in various biological processes, including digestion, immune response, and blood coagulation.

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    1. Message of nexin 1, a serine protease inhibitor, is accumulated in the follicular papilla during anagen of the hair cycle Journal of Cell Science · 1995 · 37 citations
    2. A Novel Serine Protease Overexpressed in the Hair Follicles of Nude Mice Biochemical and Biophysical Research Communications · 1999 · 32 citations
    3. Keratinocyte-Specific Onset of Serine Protease BSSP Expression in Experimental Carcinogenesis Journal of Investigative Dermatology · 2001 · 26 citations
    4. Bikunin, a Serine Protease Inhibitor, is Present on the Cell Boundary of Epidermis Journal of Investigative Dermatology · 1999 · 13 citations
    5. Growth inhibition of mouse skin tumor by serine protease inhibitor ONO-3403. PubMed · 2001 · 1 citations
    6. The Transmembrane Serine Protease HAT-like 4 Is Important for Epidermal Barrier Function to Prevent Body Fluid Loss Scientific Reports · 2017 · 19 citations
    7. The Serine Protease Activity of Corin Is Required for Normal Pigment Type Switching Journal of Investigative Dermatology · 2018 · 8 citations
    8. Delayed hair cycle in mnd2 mutant mice lacking HtrA2 serine protease activity Biochemical and Biophysical Research Communications · 2022
    9. Polygenic control of the wavy coat of the NCT mouse: involvement of an intracisternal A particle insertional mutation of the protease, serine 53 (Prss53) gene, and a modifier gene Mammalian Genome · 2022
    10. The mouse frizzy (<i>fr</i>) and rat ‘hairless’ (<i>fr</i><sup><i>CR</i></sup>) mutations are natural variants of protease serine S1 family member 8 (<i>Prss8</i>) Experimental Dermatology · 2010 · 28 citations
    11. Male balding as a major risk factor for severe COVID-19: A possible role for targeting androgens and transmembrane protease serine 2 to protect vulnerable individuals Journal of The American Academy of Dermatology · 2020 · 6 citations
    12. Matrix-Degrading Type II Transmembrane Serine Protease Matriptase: Its Role in Cancer Development and Malignancy 2006 · 12 citations
    13. Protease activity, localization and inhibition in the human hair follicle International Journal of Cosmetic Science · 2013 · 11 citations
    14. Message of protease nexin-1 is expressed in human dermal papilla cells and is affected by androgen Journal of dermatological science · 1998
    15. Matriptase: Potent Proteolysis on the Cell Surface Molecular Medicine · 2006 · 165 citations
    16. Human epidermal transglutaminase. Preparation and properties. Journal of Biological Chemistry · 1976 · 138 citations
    17. Ichthyosis, Follicular Atrophoderma, and Hypotrichosis Caused by Mutations in ST14 Is Associated with Impaired Profilaggrin Processing Journal of Investigative Dermatology · 2008 · 99 citations
    18. Human tissue kallikreins as promiscuous modulators of homeostatic skin barrier functions Biological Chemistry · 2008 · 84 citations
    19. Trypsin-induced follicular papilla apoptosis results in delayed hair growth and pigmentation Developmental Dynamics · 1997 · 29 citations
    20. Soymilk reduces hair growth and hair follicle dimensions Experimental dermatology · 2001 · 23 citations
    21. Expression of the human Cathepsin L inhibitor hurpin in mice: skin alterations and increased carcinogenesis Experimental Dermatology · 2007 · 21 citations
    22. A novel mutation in ST14 at a functionally significant amino acid residue expands the spectrum of ichthyosis-hypotrichosis syndrome Orphanet Journal of Rare Diseases · 2017 · 11 citations
    23. The Mask Mutation Identifies TMPRSS6 as an Essential Suppressor of Hepcidin Gene Expression, Required for Normal Uptake of Dietary Iron. Blood · 2007 · 9 citations
    24. Trypsin‐induced follicular papilla apoptosis results in delayed hair growth and pigmentation Developmental Dynamics · 1997 · 3 citations
    25. LEKTI: Netherton Syndrome and Atopic Dermatitis InTech eBooks · 2013 · 1 citations
    26. [A study of Nexin 1 of skin and hair follicle during postnatal development period of rat]. PubMed · 1998 · 1 citations
    27. A 20-year retrospective clinicopathologic study on melanoma in Singapore Journal of The American Academy of Dermatology · 2019
    28. PLAU and SerpinB2 role in apoptosis in leprosy Journal of The American Academy of Dermatology · 2017
    29. Netherton Syndrome Harper's Textbook of Pediatric Dermatology · 2019
    30. Bamboo Hair Syndrome or Netherton Syndrome - A Case Report IOSR journal of dental and medical sciences · 2017