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    Glossary Serine Protease Inhibitor

    blocks enzymes that cut proteins at specific sites

    A Serine Protease Inhibitor, often abbreviated as Serpin, is a type of protein that blocks the activity of serine proteases, which are enzymes that cut other proteins at specific sites. By inhibiting these enzymes, serpins play a crucial role in regulating various biological processes, including inflammation, blood clotting, and tissue remodeling.

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    1. Message of nexin 1, a serine protease inhibitor, is accumulated in the follicular papilla during anagen of the hair cycle Journal of Cell Science · 1995 · 37 citations
    2. Bikunin, a Serine Protease Inhibitor, is Present on the Cell Boundary of Epidermis Journal of Investigative Dermatology · 1999 · 13 citations
    3. Growth inhibition of mouse skin tumor by serine protease inhibitor ONO-3403. PubMed · 2001 · 1 citations
    4. Expression of the human Cathepsin L inhibitor hurpin in mice: skin alterations and increased carcinogenesis Experimental Dermatology · 2007 · 21 citations
    5. Message of protease nexin-1 is expressed in human dermal papilla cells and is affected by androgen Journal of dermatological science · 1998
    6. Protease activity, localization and inhibition in the human hair follicle International Journal of Cosmetic Science · 2013 · 11 citations
    7. LB1256 TRIV-509, a dual inhibitor of KLK5 and KLK7, rapidly improves barrier integrity and markers of epidermal differentiation in atopic dermatitis skin explants Journal of Investigative Dermatology · 2025
    8. Matrix-Degrading Type II Transmembrane Serine Protease Matriptase: Its Role in Cancer Development and Malignancy 2006 · 12 citations
    9. Human epidermal transglutaminase. Preparation and properties. Journal of Biological Chemistry · 1976 · 138 citations
    10. Soymilk reduces hair growth and hair follicle dimensions Experimental dermatology · 2001 · 23 citations
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