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Did you mean Serine Protease Inhibitor?

GlossarySerine Protease Inhibitor

blocks enzymes that cut proteins at specific sites

A Serine Protease Inhibitor, often abbreviated as Serpin, is a type of protein that blocks the activity of serine proteases, which are enzymes that cut other proteins at specific sites. By inhibiting these enzymes, serpins play a crucial role in regulating various biological processes, including inflammation, blood clotting, and tissue remodeling.

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research Nagashima-Type Palmoplantar Keratosis: A Common Asian Type Caused by SERPINB7 Protease Inhibitor Deficiency

24 citations, July 2014 in “Journal of Investigative Dermatology”

Nagashima-type palmoplantar keratosis in Asians is caused by a SERPINB7 gene mutation.

research Deficiency of the Human Cysteine Protease Inhibitor Cystatin M/E Causes Hypotrichosis and Dry Skin

10 citations, November 2018 in “Genetics in medicine”

Lack of cystatin M/E causes thin hair and dry skin.

research Deficiency of the Human Cysteine Protease Inhibitor Cystatin M/E Causes Hypotrichosis and Dry Skin

September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology”

Not having enough cystatin M/E protein causes less hair growth and dry skin.

research Protease Activity, Localization, and Inhibition in the Human Hair Follicle

11 citations, August 2013 in “International Journal of Cosmetic Science”

The study suggests that a new protease inhibitor can make hair harder to pull out, potentially reducing hair loss.

research Protease Nexin-1 Is Expressed in Human Dermal Papilla Cells and Is Affected by Androgen

March 1998 in “Journal of dermatological science”

Protease Nexin-1 is found in human hair growth cells and is affected by male hormones.

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community Adrogens and Covid-19

in Treatment 7 upvotes 4 years ago

The possible increased risk of severe Covid-19 cases in men due to higher androgen levels, and how taking medications such as finasteride, dutasteride, spironolactone, enzalutamide, or canabidiol might help mitigate the severity of the disease.