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GlossarySerine Protease

enzyme that breaks down proteins by cleaving peptide bonds

Serine proteases, also known as serine endopeptidases, are a group of enzymes that break down proteins by cleaving peptide bonds. They are named for the serine residue in their active site, which plays a crucial role in the catalytic process. These enzymes are involved in various biological processes, including digestion, immune response, and blood coagulation.

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research Delayed Hair Cycle in Mnd2 Mutant Mice Lacking HtrA2 Serine Protease Activity

December 2022 in “Biochemical and Biophysical Research Communications”

HtrA2 activity is crucial for normal hair growth by regulating fat cell development.

research Protease Activity, Localization, and Inhibition in the Human Hair Follicle

11 citations, August 2013 in “International Journal of Cosmetic Science”

The study suggests that a new protease inhibitor can make hair harder to pull out, potentially reducing hair loss.

research Protease Nexin-1 Is Expressed in Human Dermal Papilla Cells and Is Affected by Androgen

March 1998 in “Journal of dermatological science”

Protease Nexin-1 is found in human hair growth cells and is affected by male hormones.

research The CAP1/Prss8 Catalytic Triad Is Not Involved in PAR2 Activation and Protease Nexin-1 (PN-1) Inhibition

14 citations, August 2014 in “The FASEB Journal”

CAP1/Prss8 does not activate PAR2 or inhibit PN-1.

research Soymilk Reduces Hair Growth And Hair Follicle Dimensions

23 citations, December 2001 in “Experimental dermatology”

Soymilk can slow hair growth and make hair thinner.

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community Help in Germany to get recommended medicine

in Finasteride/Dutasteride 5 upvotes 3 months ago

A user in Germany is seeking advice on obtaining Dutasteride, Minoxidil, and Biotin for hair treatment before a hair transplant. They face difficulties getting prescriptions and are concerned about delays due to required exams.

community Getting dutasteride in germany

in Finasteride/Dutasteride 18 upvotes 4 months ago

You can get dutasteride in Germany through the Teleclinic app, which sends a prescription to a nearby pharmacy. It costs around 18-19 euros for the prescription and 47 euros for 90 pills of Avodart 0.5.

community 1.5 years on fin and min (24 yo). Start early guys, it’s worth it.

in Progress Pictures 1167 upvotes 1 year ago

The conclusion of the conversation is that the user "CheckHopeful" has seen significant improvement in their hair loss after using finasteride and minoxidil for 1.5 years. Some users discuss side effects and suggest adjusting the dosage or trying topical finasteride or RU58841.