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    Glossary Plasminogen Activator Inhibitor-1

    regulates blood clot breakdown by inhibiting plasminogen conversion enzymes

    Plasminogen Activator Inhibitor-1 (PAI-1) is a protein that regulates the breakdown of blood clots by inhibiting enzymes that convert plasminogen to plasmin, which is responsible for clot degradation. Elevated levels of PAI-1 are associated with an increased risk of thrombosis and various cardiovascular diseases, as it can lead to excessive clot formation.

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    Research 10 of 355

    1. Role of plasminogen activator inhibitor type 1 (PAI-1) in PCOS patient International journal of reproduction, contraception, obstetrics and gynecology · 2017 · 3 citations
    2. Oral contraceptive pill (OCP) treatment alters the gene expression of intercellular adhesion molecule-1 (ICAM-1), tumor necrosis factor-α (TNF-α), monocyte chemoattractant protein-1 (MCP-1) and plasminogen activator inhibitor-1 (PAI-1) in polycystic ovary syndrome (PCOS) women compared to drug-naive PCOS women BMC women's health · 2023 · 2 citations
    3. Thrombin activatable fibrinolysis inhibitor and other hemostatic parameters in patients with polycystic ovary syndrome Gynecological Endocrinology · 2009 · 29 citations
    4. Wound healing in development Birth Defects Research · 2012 · 29 citations
    5. Evaluation of cardiac risk marker levels in obese and non-obese patients with polycystic ovaries Gynecological Endocrinology · 2016 · 21 citations
    6. Proteomics Characterization of Primary Human Oral Epithelial Cells Using a Novel Culture Technique for Use in Tissue Regeneration MOJ proteomics & bioinformatics · 2015
    7. Urokinase plasminogen activator (uPA) is a positive regulator of outer root sheath keratinocyte proliferation Cell Biology International · 2004 · 2 citations
    8. Localization of Plasminogen Activator Inhibitor Type 2 (PAI-2) in Hair and Nail: Implications for Terminal Differentiation 1998 · 42 citations
    9. Ku80 as a Novel Receptor for Thymosin β4 That Mediates Its Intracellular Activity Different from G-actin Sequestering Journal of Biological Chemistry · 2007 · 37 citations
    10. Urokinase is a Positive Regulator of Epidermal Proliferation In Vivo Journal of Investigative Dermatology · 1999 · 28 citations
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