27 citations
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March 2019 in “PLoS ONE” This study suggests that Thyroxine (T4) may promote key features of human skin wound healing, such as re-epithelialization and angiogenesis, in an ex vivo model.
January 2024 in “Surgical & Cosmetic Dermatology” This review discusses recent research on exosomes' role in dermatology, highlighting their involvement in skin diseases and rejuvenation and exploring therapeutic possibilities in these areas.
49 citations
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February 2019 in “The Journal of Clinical Endocrinology and Metabolism” This review offers evidence-based recommendations for diagnosing and treating female pattern hair loss, emphasizing clinical assessment and starting treatment with minoxidil, while noting that measurement of certain hormones and vitamins is optional.
22 citations
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August 2015 in “PloS one” This study found that the binding and release of BMP-2 from kerateine biomaterials are significantly influenced by pH and salt concentration, highlighting the potential for developing improved bone repair systems.
17 citations
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January 2019 in “Annals of Dermatology” This study found that higher serum CXCL10 levels may predict the progression of non-segmental vitiligo, especially in patients also suffering from autoimmune thyroid disease and/or alopecia areata.
3 citations
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June 2023 in “Frontiers in Medicine” This study constructed a model using serum levels of BMP2, CD8A, PRF1, and XCL1 as a non-invasive biomarker to accurately predict recurrence in patients with alopecia areata.
1 citations
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December 2023 in “Diagnostics” This review discussed the variability in measuring serum testosterone levels and emphasized the need for standardizing testing and sharing updated treatment protocols to manage male hypogonadism effectively. It also highlighted the importance of considering secondary hypogonadism causes and suggested consulting with endocrinologists for optimal management.
April 2025 in “Frontiers in Immunology” This case report describes significant therapeutic effects from Tofacitinib Citrate Sustained-Release Tablets in a patient with Alopecia Areata, while highlighting the economic burden of long-term treatment.
January 2025 in “Biomaterials Research” This study developed a novel zinc-releasing hydrogel, Zn-Gel, which promoted wound healing by controlling zinc ion release and demonstrated excellent compatibility and efficacy in enhancing cell proliferation, blood vessel formation, and tissue regeneration in vitro and in vivo settings.
November 2024 in “Journal of Cosmetic Dermatology” This study observed that a topical serum containing Silybum marianum extract, manganese PCA, and Lespedeza capitata extract enhanced hair follicle growth and hair shaft elongation, while prolonging the anagen phase in an ex vivo human scalp skin model, suggesting potential benefits for hair loss treatment.
This study found a significant association between higher serum anti-thyroperoxidase (anti-TPO) antibody levels and the occurrence of chronic spontaneous urticaria, suggesting that testing for anti-TPO antibodies alongside primary thyroid markers might be important in managing this condition.
4 citations
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May 2022 in “Future Journal of Pharmaceutical Sciences” This study found that a melatonin-loaded microemulsion exhibited controlled release and significant stratum corneum deposition in ex vivo permeation tests, suggesting its potential for further evaluation in treating androgenic alopecia.
89 citations
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January 2021 in “Molecules” This review discusses the applications of biopolymeric composites in controlled drug release, tissue engineering, and wound healing, but reports no new experimental results, highlighting the need for further development and analysis.
16 citations
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January 2019 in “Pharmaceutical biology” This study found that Lespedeza cuneata aqueous extract reduced serum dihydrotestosterone levels and 5α-reductase mRNA expression in testosterone-induced prostatic hyperplasia in rats, suggesting potential as a treatment for prostatic hyperplasia.
6 citations
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May 2023 in “Dermatology Research and Practice” This study observed that patients with alopecia areata had significantly higher serum levels of IL-15 and TNF-α compared to controls, with TNF-α levels particularly elevated in individuals with alopecia totalis, though these biomarkers were not influenced by disease duration or activity.
3 citations
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December 2023 in “International Journal of Nanomedicine” Repaglinide-loaded liponiosomal hybrids improve blood sugar control and insulin release better than regular Repaglinide.
1 citations
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January 2024 in “Theranostics” This source reviews the role of exosomes in regenerative medicine, highlighting their ability to mediate cell communication and transport biomolecules to enhance or impair biological functions, with potential applications in tissue repair and regeneration.
This study reports that subcutaneous testosterone pellets in peri- and postmenopausal women provided sustained hormone release and potential benefits for sexual function, but raised concerns about safety, variability, and dosing inconsistencies.
February 2018 in “Zenodo (CERN European Organization for Nuclear Research)” This study observed that administering 1000 mg/kg of LSFP significantly reduced serum FSH and LH levels and testicular index in male Wistar rats, while lower doses showed no such effect.
1 citations
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January 2020 in “Refubium (Universitätsbibliothek der Freien Universität Berlin)” This thesis explored how stratum corneum barrier disruption and pH-sensitive nanoparticles influence drug penetration and release in skin models, highlighting potential applications for treating atopic dermatitis.
254 citations
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September 2014 in “Menopause” The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.
14 citations
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February 2025 in “Pharmaceutics” This review highlights recent advancements in using niosomes as nanocarriers for improved delivery and sustained release of active cosmetic compounds, discussing their properties, applications, and future potential in cosmetic chemistry.
8 citations
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January 2024 in “Regenerative Biomaterials” This study found that a novel bioceramic/alginate hydrogel with photothermal properties and multiple ion release effectively reduces infection and inflammation, and enhances osseointegration in early-stage peri-implant lesions, potentially improving dental implant survival rates.
3 citations
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October 2024 in “Advances in Therapy” In this study, Chinese children with central precocious puberty receiving 6-monthly injections of triptorelin showed luteinizing hormone suppression and slowed development of sexual characteristics over 12 months, without severe adverse events, suggesting it may be an effective treatment option for this population.
September 2025 in “Scientific periodicals of Ukraine” This study found that a 3-month treatment with metformin significantly reduced serum luteinizing hormone, FSH, and testosterone concentrations in women with PCOS.
77 citations
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January 2015 in “International Journal of Biological Macromolecules” This study developed minoxidil sulphate-loaded chitosan nanoparticles that doubled drug delivery to hair follicles in vitro compared to a control solution, suggesting potential for improved alopecia treatment.
66 citations
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January 2017 in “Acta dermato-venereologica” This review suggests that isotretinoin's effects on severe acne and various cancers may result from apoptosis, which might also explain its adverse effects through genetic variability.
51 citations
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November 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, researchers found that while both beard and scalp dermal papilla cells release similar autocrine growth factors, only beard cells increased production and response with testosterone, suggesting these factors enhance androgen-induced hair growth.
25 citations
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March 2000 in “Journal of Endocrinological Investigation” Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.
1 citations
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February 2023 in “Pharmaceutics” This study suggests that UVA-responsive nanocapsules may provide an effective method for skin antisepsis by releasing ethanol and reducing microorganisms within hair follicles on ex vivo porcine ear skin.