Adult Male Hypogonadism: A Laboratory Medicine Perspective on Its Diagnosis and Management

    December 2023 in “ Diagnostics ”
    Mark Livingston, Adrian Heald
    TLDR Accurate testosterone measurement and standardized lab practices are crucial for diagnosing and managing adult male hypogonadism.
    The document provides a detailed examination of adult male hypogonadism, emphasizing the critical role of accurate testosterone (T) measurement and the need for standardized laboratory practices. It highlights the condition's prevalence, affecting 6-12% of the general male population and up to 40% of men with type 2 diabetes, and its association with increased mortality and cardiovascular disease. The review underscores the importance of considering secondary causes and recommends a comprehensive management approach, including lifestyle changes and testosterone replacement therapy (TRT) for symptomatic men with low T levels. The document also addresses the impact of COVID-19 on T levels and the need for precise laboratory methodologies to support clinical decisions. It calls for harmonized T reference intervals and treatment thresholds to improve patient outcomes and reduce clinical confusion.
    Discuss this study in the Community →

    Research cited in this study

    2 / 2 results

    Related Community Posts Join

    6 / 1000+ results

      community Any other celebrities known to be taking finasteride ?

      in Finasteride/Dutasteride  455 upvotes 1 year ago
      The conversation discusses various celebrities who reportedly use hair loss treatments like finasteride and dutasteride. Users share their experiences and opinions on starting treatment, with some encouraging the original poster to consult a dermatologist and consider treatment before it's too late.

      community Minoxidil + Gym + Cutting. Is it bad?

      in Minoxidil  40 upvotes 2 years ago
      A user is concerned about weight loss stagnation while using minoxidil and finasteride during a calorie-cutting diet. Responses suggest water retention or a weight loss plateau as possible causes.

      community 8 week - sharing Finasteride blood test update

      in Progress Pictures  6 upvotes 2 years ago
      A 32-year-old male started taking 0.5mg of finasteride daily for hair thinning and, after 8 weeks, experienced a 70% reduction in DHT and an increase in estradiol; he is currently in the shedding phase of treatment and questioning if the dosage is correct based on his DHT levels. He began with a lower dose due to already low normal testosterone and DHT levels.

    Similar Research

    5 / 1000+ results