Cuprorivaite/Hardystonite/Alginate Composite Hydrogel with Thermionic Effect for the Treatment of Peri-Implant Lesion

    January 2024 in “ Regenerative Biomaterials ”
    Yiru Xia, Zhaowenbin Zhang, Kecong Zhou, Zhikai Lin, Rong Shu, Yuze Xu, Zhen Zeng, Jiang Chang, Yufeng Xie
    Studysummary This study found that a novel bioceramic/alginate hydrogel with photothermal properties and multiple ion release effectively reduces infection and inflammation, and enhances osseointegration in early-stage peri-implant lesions, potentially improving dental implant survival rates. Our plain-language summary of this paper — not a Tressless recommendation.
    The study explores a novel cuprorivaite/hardystonite/alginate composite hydrogel for treating peri-implant lesions, emphasizing its antibacterial and biological properties. The hydrogel, particularly effective when combined with near-infrared (NIR) laser irradiation, enhances osseointegration and reduces inflammation by releasing bioactive ions (Cu2+, Zn2+, and SiO32−) and utilizing photothermal effects. In a rat model with 36 subjects, the Cu–Zn hydrogel with NIR treatment showed the highest implant survival rate of 83.33%, significantly reducing bacterial content and promoting bone integration. The study concludes that this hydrogel, with its thermionic effects, is a promising treatment for improving implant integration amidst periodontal inflammation.
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