TLDR The hydrogel helps heal skin injuries by promoting blood vessel and hair growth.
The study developed an injectable composite hydrogel by crosslinking glycol chitosan with silica nanoparticles, which served as a wound dressing with strong tissue adhesion properties. This hydrogel could be directly applied to wound sites, filling the area and acting as a carrier for proteins and cells. The encapsulation of fibroblasts within the hydrogel showed promising results in treating full-thickness skin defects in a mouse model, promoting the growth of hair follicles and microvessels, and reducing scar formation. The hydrogel demonstrated a lap-shear stretching force of approximately 90 kPa, indicating its strong adhesive capabilities.
150 citations
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June 2014 in “Biomaterials” Peptide hydrogels heal burn wounds faster and better than standard dressings.
527 citations
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December 2011 in “Proceedings of the National Academy of Sciences” Dextran hydrogels improve burn wound healing and skin regeneration.
2 citations
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June 2023 in “Gels” Injectable hydrogels are becoming increasingly useful in medicine for drug delivery and tissue repair.
26 citations
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November 2022 in “European journal of medical research” Nanoparticles can effectively treat diseases by modifying blood vessel growth.
1 citations
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November 2023 in “Polymers” Polyurethane dressings show promise for wound healing but need improvements to adapt better to the healing process.
119 citations
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March 2020 in “Frontiers in Bioengineering and Biotechnology” Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.
April 2024 in “Journal of composites science” Hydrogel composites have great potential in regenerative medicine, tissue engineering, and drug delivery.
