Effective Treatment of Intractable Diseases Using Nanoparticles to Interfere with Vascular Supply and Angiogenic Process

The document discussed the use of nanoparticles (NPs) to effectively modify angiogenesis processes, either by enhancing or suppressing them, to treat various disorders associated with angiogenesis. Traditional angiogenic therapies faced limitations such as limited bioavailability, drug resistance, and nonspecificity. However, recent advancements in the use of inorganic or organic NPs showed promise in overcoming these challenges. The article covered the application of NPs in encouraging tissue vascularization and their effects in treating conditions like bone regeneration, peripheral vascular disease, diabetic retinopathy, ischemic stroke, rheumatoid arthritis, and cancer. It also addressed the challenges and future potential of NPs in treating angiogenesis-related diseases.