Inorganic Nanomaterial for Biomedical Imaging of Brain Diseases

The review discussed the potential of inorganic nanomaterials to enhance biomedical imaging for brain diseases by addressing limitations of traditional methods like MRI and CT. These nanomaterials, due to their unique properties, could improve targeting and accuracy in imaging brain disease regions, including tumors, trauma, vascular, and neurodegenerative diseases. The document explored the use of various nanomaterials, such as silicon-based, iron-based, and manganese-based, for their stable structure, biocompatibility, and ability to enhance imaging signals. It highlighted innovative approaches to overcome the blood-brain barrier for better drug delivery and treatment efficacy, particularly in diseases like Alzheimer's, Parkinson's, and ischemic stroke. Despite progress, challenges in biocompatibility, safety, and clinical translation remained, emphasizing the need for further research to transition these technologies from laboratory to clinical applications.