Significant Efficacy of Tofacitinib from China in the Treatment of Alopecia Areata: A Case Report

    April 2025 in “ Frontiers in Immunology ”
    Yijia He, Jinxu Qi, Zhuochen Wu … Guoqiang Zhang
    Studysummary This case report describes significant therapeutic effects from Tofacitinib Citrate Sustained-Release Tablets in a patient with Alopecia Areata, while highlighting the economic burden of long-term treatment.
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    Research cited in this study 20

    1. Efficacy And Safety Of Ritlecitinib In Asian Patients With Alopecia Areata: A Subgroup Analysis Of The ALLEGRO Phase 2b/3 Trial The Journal of Dermatology · 2025
    2. Efficacy and Safety of the Oral Janus Kinase 3/Tyrosine Kinase Inhibitor Ritlecitinib Over 24 Months: Integrated Analysis of the ALLEGRO Phase IIb/III and Long-Term Phase III Clinical Studies in Alopecia Areata British Journal of Dermatology · 2024
    3. Baricitinib Withdrawal and Retreatment in Patients With Severe Alopecia Areata JAMA Dermatology · 2024
    4. Comparative Efficacy and Safety of JAK Inhibitors in the Treatment of Moderate-to-Severe Alopecia Areata: A Systematic Review and Network Meta-Analysis Frontiers in pharmacology · 2024
    5. Upadacitinib for Alopecia Areata in Different Backgrounds: A Case Series Clinical, cosmetic and investigational dermatology · 2024
    6. Long-Term Efficacy and Safety of Baricitinib in Patients With Severe Alopecia Areata: 104-Week Results From BRAVE-AA1 and BRAVE-AA2 Journal of the European Academy of Dermatology and Venereology · 2024
    7. Effectiveness and Predictive Factors of Response to Tofacitinib Therapy in 125 Patients with Alopecia Areata: A Single-Centre Real-World Retrospective Study Acta dermato-venereologica · 2023
    8. Treatments for Moderate-to-Severe Alopecia Areata: A Systematic Narrative Review Dermatology and therapy · 2023
    9. Efficacy and Safety of Baricitinib in Patients With Alopecia Areata: Evidence to Date Drugs in context · 2023
    10. Real-Life Effectiveness and Tolerance of Baricitinib for the Treatment of Severe Alopecia Areata with 1-Year Follow-Up Data Dermatology and Therapy · 2023
    11. Alopecia Areata: Current Treatments and New Directions American Journal of Clinical Dermatology · 2023
    12. Successful Treatment of Alopecia Universalis With Abrocitinib: A Case Report Journal of Dermatological Treatment · 2023
    13. Alopecia Areata: An Update on Etiopathogenesis, Diagnosis, and Management Clinical Reviews in Allergy & Immunology · 2021
    14. Alopecia Areata: A Review on Diagnosis, Immunological Etiopathogenesis, and Treatment Options Clinical and Experimental Medicine · 2021
    15. Benefit and Risk Profile of Tofacitinib for the Treatment of Alopecia Areata: A Systematic Review and Meta-Analysis Journal of the European Academy of Dermatology and Venereology · 2019
    16. JAK-Inhibitors in Dermatology: Current Evidence and Future Applications Journal of dermatological treatment · 2018
    17. Alopecia Areata: Treatment Options and Efficacy Journal of the American Academy of Dermatology · 2017
    18. Alopecia Areata Is Driven by Cytotoxic T Lymphocytes and Is Reversed by JAK Inhibition Nature medicine · 2014
    19. Alopecia Areata: An Autoimmune Disease Causing Hair Loss The New England Journal of Medicine · 2012
    20. Interventions for Alopecia Areata Cochrane library · 2008

    Related research 2

    1. Twenty Nail Dystrophy with Alopecia Areata in an Atopic Child International journal of research in dermatology · 2019
    2. Successful Treatment of Severe Alopecia Areata With Oral or Topical Tofacitinib PubMed · 2018