Upadacitinib for Alopecia Areata in Different Backgrounds: A Case Series

    March 2024 in “ Clinical, cosmetic and investigational dermatology ”
    Xiaofu He, Dongyue Yang, Lee Min Lai … Min Xiao
    Studysummary This study reported that five patients with alopecia areata achieved satisfactory results using 15 mg of Upadacitinib daily after conventional treatments had failed, without experiencing adverse events.
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    Research cited in this study 15

    1. Alopecia Areata: Current Treatments and New Directions American Journal of Clinical Dermatology · 2023
    2. Upadacitinib for Management of Recalcitrant Alopecia Areata: A Retrospective Case Series JAAD case reports · 2023
    3. Treatment of Alopecia Areata With the Janus Kinase Inhibitor Upadacitinib: A Retrospective Cohort Study Journal of the American Academy of Dermatology · 2023
    4. Alopecia Universalis in an Adolescent Successfully Treated with Upadacitinib: A Case Report and Review of the Literature on the Use of JAK Inhibitors in Pediatric Alopecia Areata Dermatology and therapy · 2023
    5. Emerging Drugs for the Treatment of Alopecia Areata Expert opinion on emerging drugs · 2022
    6. Alopecia Areata: An Update on Etiopathogenesis, Diagnosis, and Management Clinical Reviews in Allergy & Immunology · 2021
    7. A Randomized Placebo-Controlled Single-Center Pilot Study of the Safety and Efficacy of Apremilast in Subjects with Moderate-to-Severe Alopecia Areata Archives of dermatological research · 2018
    8. An Open-Label Pilot Study to Evaluate the Efficacy of Tofacitinib in Moderate to Severe Patch-Type Alopecia Areata, Totalis, and Universalis Journal of Investigative Dermatology · 2018
    9. Alopecia Areata: Overview and Insights from January 2018 Journal of The American Academy of Dermatology · 2017
    10. Safety and Efficacy of the JAK Inhibitor Tofacitinib Citrate in Patients with Alopecia Areata JCI insight · 2016
    11. Oral Ruxolitinib Induces Hair Regrowth in Patients with Moderate-to-Severe Alopecia Areata JCI insight · 2016
    12. Reversal of Alopecia Areata Following Treatment With the JAK1/2 Inhibitor Baricitinib EBioMedicine · 2015
    13. Inhibiting Janus Kinases to Treat Alopecia Areata Nature medicine · 2014
    14. Alopecia Areata Is Driven by Cytotoxic T Lymphocytes and Is Reversed by JAK Inhibition Nature medicine · 2014
    15. Efficacy And Safety Of A New Clobetasol Propionate 0.05% Foam In Alopecia Areata: A Randomized, Double-Blind Placebo-Controlled Trial Journal of the European Academy of Dermatology and Venereology · 2006

    Related research 1

    1. Twenty Nail Dystrophy with Alopecia Areata in an Atopic Child International journal of research in dermatology · 2019