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research Cortexolone 17α-Propionate (Clascoterone) is an Androgen Receptor Antagonist in Dermal Papilla Cells In Vitro
This study found that cortexolone 17α-propionate (clascoterone) effectively inhibited androgen receptor-regulated transcription and IL-6 synthesis in scalp cells, potentially making it a promising candidate for topical treatment of androgenetic alopecia.
research Anatomical development of the skin in foetuses of Red Sokoto goats (Capra hircus)
This study found that the prenatal skin development in Red Sokoto goats undergoes significant morphological changes across gestational stages, which may be important for their adaptation and thermoregulation after birth.
research The place of intralesional steroid therapy in dermatology
This article reviews the use of intralesional steroid therapy in dermatology, highlighting its application in conditions like nail disorders and cystic acne, but it reports no new clinical results.
research Enhancement of drug permeation across skin through stratum corneum ablation
This source discusses using stratum corneum ablation as a promising method to enhance transdermal drug delivery by temporarily removing the skin's outermost barrier to improve medication absorption.
research Alopecia Totalis
This case report describes hair regrowth in a patient with alopecia totalis using fluocinolone acetonide cream applied under thin plastic films.
research Triamcinolone Acetonide Mesotherapy in the Treatment of Recalcitrant Patches of Alopecia Areata - A Pilot Study
This article reviews alopecia areata treatments, noting varied outcomes, and reports no new clinical results.
research Calcipotriol Plus Betamethasone Dipropionate Aerosol Foam For Scalp Psoriasis
In this article, the authors reported that calcipotriol/betamethasone dipropionate aerosol foam significantly improved scalp psoriasis symptoms in three patients by reducing itching and improving flaky patches within a four-week treatment period, confirming its efficacy and enhanced skin penetration compared to older formulations.
research RETRACTION: Sonographic Comparison of Subcutaneous Fat Layer Thickness in the Scalp Area in Patients With Androgenetic Alopecia Compared to Healthy Individuals: Cross‐Sectional
research Ex-vivo measurement of scalp follicular infundibulum delivery of zinc pyrithione and climbazole from an anti-dandruff shampoo
In this study, researchers developed a method using scalp cyanoacrylate biopsy and advanced imaging techniques to effectively measure and visualize the distribution of anti-dandruff shampoo ingredients zinc pyrithione and climbazole within the scalp follicular infundibulum.
research Alopecia prevention during chemotherapy: from the benchmark to real clinical practice. A prospective study
In this study, researchers found that using the Orbis II scalp cooling device in a single-center setting effectively prevented severe chemotherapy-induced alopecia in 73% of patients with various cancer types, though the authors recommend further studies to explore broader applicability and influencing factors.
research THE ENTRY OF CA45 INTO THE SKIN AND OTHER SOFT TISSUES OF THE RAT: AN AUTORADIOGRAPHIC AND SPODOGRAPHIC STUDY
This study demonstrated radiocalcium uptake in skin, eye, cartilage, and mucous glands, with the highest concentration in the hair follicle's keratogenous zone.
research Evaluation of the efficacy of transdermal drug delivery of calcipotriol plus betamethasone versus tacrolimus in the treatment of vitiligo
This study found that microneedling combined with calcipotriol plus betamethasone was more effective in treating vitiligo than microneedling with tacrolimus, particularly in difficult-to-treat areas.
research Enhancing Lower Extremity Defect Coverage: High Viability Ultra-Thin Split-Thickness Skin Grafts Obtained from the Scalp
This study found that using autologous ultra-thin split-thickness skin grafts from the scalp with the DermaBlade tool led to rapid wound healing, minimal complications, and improved cosmetic outcomes for 90% of patients with lower extremity lesions, without causing scarring or alopecia.
research An efficient method for eccrine gland isolation from human scalp
This study describes a method inspired by hair transplantation techniques to efficiently isolate eccrine sweat glands from human scalp hair grafts, potentially facilitating further research into their function.
research Scalp Dermatology for the Hair Restoration Surgeon
This abstract suggests that sun damage may thin scalp tissue, potentially affecting hair transplant outcomes due to increased risk of necrosis or poor growth.
research Scabies with Secondary Infection Resembling Kerion-Type Tinea Capitis
This case report describes an 8-year-old boy with impetigenic scabies on his scalp, which responded well to treatment with topical permethrin, oral antihistamines, and antibiotics.
research Dorsal Skin Reactions of Hairless Dogs to Topical Treatment with Corticosteroids
This study suggests that hairless dogs' skin shows sensitivity to topical corticosteroids, highlighting their potential as a model for studying the efficacy and adverse effects of these treatments on skin.
research Management of Chemotherapy-Induced Alopecia With Scalp Cooling
This study found that scalp cooling effectively reduces chemotherapy-induced hair loss, especially with taxane-based regimens, and recent U.S. trials support its safety, despite logistical and insurance challenges.
research Exploring the Chorioallantoic Membrane (CAM) as a Platform for Burn Wound Modelling and Analysis
This study supports the use of the chicken chorioallantoic membrane as an effective pre-clinical model for burn wound research and the screening of new therapeutic agents.
research Mesotherapy with bicalutamide: A new treatment for androgenetic alopecia
This study found that bicalutamide mesotherapy resulted in subtle hair density improvements and was well tolerated by premenopausal women with androgenetic alopecia.
research Efficacy and Safety of Topical Corticosteroid Treatment under Occlusion for Severe Alopecia Areata in Children. A single-center retrospective analysis
This study suggests that potent topical corticosteroid occlusion may be a safe and effective treatment option for pediatric patients with severe alopecia areata, although further research is needed on its long-term safety and recurrence.
research Efficacy of superficial cryotherapy on the eyebrows of patients with alopecia universalis also treated with contact immunotherapy on the scalp: a prospective, split‐face comparative study
This study found that superficial cryotherapy significantly increased hair density and thickness in treated eyebrows compared to untreated controls after 5 months in patients with alopecia areata.
research Topical Calcipotriol for Preventive Treatment of Hypertrophic Scars
This study reported that topical calcipotriol did not reduce hypertrophic scar formation in women post reduction mammoplasty, but found a strong association between activated keratinocytes and scar formation.
research Side gland of Suncus murinus as a new model of sebaceous gland: 5?-reductase, androgen receptor, and nuclear androgen content in male and female animals
The side gland of Suncus murinus is a good model for studying human sebaceous glands.
research 710 Use of mass spectrometry imaging and a full thickness 3D skin equivalent for evaluation of percutaneous absorption
This study found that retinoic acid and a retinol complex formulation showed different permeation and compound localization in a skin equivalent model, with unique lipid changes observed with only the retinol formulation.
research Treatment Outcomes of Triamcinolone Acetonide Compared with Cryotherapy in Alopecia Areata: Evidence from a Systematic Review and Meta-Analysis
In a systematic review and meta-analysis, the researchers found that intralesional triamcinolone acetonide was more effective than cryotherapy for achieving significant hair regrowth in patients with patchy alopecia areata, although both treatments had distinct safety profiles.
research Лесоведение и лесоводство. Термины, понятия, определения
This study developed a grooved microneedle platform enabling precise transdermal delivery of triamcinolone acetonide for alopecia areata, achieving accurate dosing by controlling groove position and drug concentration.
research Topical calcipotriol mixed with topical steroid versus topical steroid alone in treatment of alopecia areata
This study investigated the efficacy and safety of a gel combining topical calcipotriol and steroid for alopecia areata. It found the combination worked similarly to steroids alone in reducing hair loss, but with fewer side effects.
research Application of Ostrich Antibodies to the Restoration of Hair Growth, a Preliminary and Case Report
This study found that ostrich antibodies targeting dihydrotestosterone and 5α-reductase, when combined with antibodies against harmful skin bacteria, may effectively promote hair regrowth in androgenetic alopecia cases.