Alopecia Prevention During Chemotherapy: From the Benchmark to Real Clinical Practice. A Prospective Study

February 2024 in “ Journal of Modern Oncology ”

Marina A. Lyadova, Tatiana A. Nersesova, Anastasia A. Zhuravleva, Denis S. Fedorinov, Anna A. Dudnik, E. A. Denisova, M. V. Nosova, O. A. Pardabekova, Kristina N. Lisitsyna, Veronika Tuleiko, Olesya A. Bikmurzina

alopecia chemotherapy-induced alopecia scalp cooling scalp hypothermia Orbis II scalp cooling device hair loss chemotherapy hair loss cold cap

TLDR Scalp cooling effectively prevents hair loss during chemotherapy in most cases.

The study evaluated the effectiveness of the Orbis II scalp cooling device in preventing chemotherapy-induced alopecia in 51 patients with various cancer types. Conducted from June 2022 to May 2023, the study found that scalp hypothermia was effective in preventing severe alopecia in 73% of cases, with the majority of procedures performed on female patients with breast, ovarian, and cervix cancers. The results suggest that scalp cooling is an effective method for alopecia prevention during chemotherapy, though further research with larger patient populations is needed to better understand factors influencing its effectiveness.

View this study on modernonco.orscience.ru →

Discuss this study in the Community →

Research cited in this study

9 / 9 results

research Prevention and Treatment of Chemotherapy-Induced Alopecia: What Is Available and What Is Coming?

4 citations , March 2023 in “Current Oncology”

Scalp cooling is the only FDA-approved method to prevent hair loss from chemotherapy, but other treatments like minoxidil and PRP are being tested.

research Identifying the Supportive Care Needs of Men and Women Affected by Chemotherapy-Induced Alopecia: A Systematic Review

19 citations , July 2020 in “Journal of cancer survivorship”

People undergoing chemotherapy need better support and information to cope with hair loss.

research Assessment of Quality of Life and Treatment Outcomes of Patients With Persistent Postchemotherapy Alopecia

43 citations , March 2019 in “JAMA Dermatology”

Hair regrowth treatments had modest benefits for patients with long-term hair loss after chemotherapy.

research Permanent Chemotherapy-Induced Alopecia in Patients with Breast Cancer: A 3-Year Prospective Cohort Study

59 citations , August 2018 in “The oncologist”

Some breast cancer patients still experience hair loss three years after chemotherapy, especially with taxane-based treatments.

research A Clinical and Biological Guide for Understanding Chemotherapy-Induced Alopecia and Its Prevention

38 citations , September 2017 in “Oncologist”

Scalp cooling can help prevent chemotherapy-induced hair loss with a 50-90% success rate and is safe for patients.

research Results of Scalp Cooling During Anthracycline-Containing Chemotherapy Depend on Scalp Skin Temperature

21 citations , September 2016 in “Breast”

Cooler scalp temperatures during chemotherapy may prevent hair loss.

research Pathobiology of Chemotherapy-Induced Hair Loss

218 citations , January 2013 in “The Lancet Oncology”

Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.

research Protection Against Chemotherapy-Induced Alopecia

97 citations , September 2006 in “Pharmaceutical Research”

No treatment fully prevents hair loss from chemotherapy yet.

research Minoxidil as a Prophylaxis of Doxorubicin-Induced Alopecia

49 citations , October 1994 in “Annals of Oncology”

Minoxidil not effective in preventing chemotherapy-induced hair loss.

Similar Research

5 / 1000+ results

research Scalp Hypothermia for the Prevention of Chemotherapy-Induced Alopecia in Breast Cancer

1 citations , February 2024 in “Journal of Modern Oncology”

Scalp cooling helps prevent hair loss during chemotherapy for breast cancer.

research Scalp Hypothermia as a Preventative Measure for Chemotherapy-Induced Alopecia: A Review of Controlled Clinical Trials

37 citations , October 2017 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”

Scalp cooling effectively reduces hair loss from chemotherapy.

research Presentation, Impact and Prevention of Chemotherapy-Induced Hair Loss: Scalp Cooling Potentials and Limitations

62 citations , February 2011 in “Expert review of dermatology”

Scalp cooling can reduce chemotherapy-induced hair loss and should be available in all hospitals.

research Hair Disorders in Patients with Cancer

53 citations , April 2018 in “Journal of The American Academy of Dermatology”

Cancer treatments often cause hair disorders, significantly affecting patients' quality of life, and better management methods are needed.

research A Clinical and Biological Guide for Understanding Chemotherapy-Induced Alopecia and Its Prevention

38 citations , September 2017 in “Oncologist”

Scalp cooling can help prevent chemotherapy-induced hair loss with a 50-90% success rate and is safe for patients.

Alopecia Prevention During Chemotherapy: From the Benchmark to Real Clinical Practice. A Prospective Study

Research cited in this study

research Prevention and Treatment of Chemotherapy-Induced Alopecia: What Is Available and What Is Coming?

research Identifying the Supportive Care Needs of Men and Women Affected by Chemotherapy-Induced Alopecia: A Systematic Review

research Assessment of Quality of Life and Treatment Outcomes of Patients With Persistent Postchemotherapy Alopecia

research Permanent Chemotherapy-Induced Alopecia in Patients with Breast Cancer: A 3-Year Prospective Cohort Study

research A Clinical and Biological Guide for Understanding Chemotherapy-Induced Alopecia and Its Prevention

research Results of Scalp Cooling During Anthracycline-Containing Chemotherapy Depend on Scalp Skin Temperature

research Pathobiology of Chemotherapy-Induced Hair Loss

research Protection Against Chemotherapy-Induced Alopecia

research Minoxidil as a Prophylaxis of Doxorubicin-Induced Alopecia

Related Community Posts Join

community Is it possible to create an estrogen mesotherapy/topical that doesn't go systemic?

community 6 week update fellas, 5mg oral minoxidil. Pics are 2nd June – 10th July

community Finally, some real breakthroughs. A comparison of the two leading baldness treatments: PP405 versus ABS-201

community PP405: The Ultimate Hair Loss Drug for Complete Hair Growth

community DUPA VS. FAPD, which is more treatable? Which is worse?

community Why Fin/Dut is always recommended. The top 10 reasons for hairloss in men.

Similar Research

research Scalp Hypothermia for the Prevention of Chemotherapy-Induced Alopecia in Breast Cancer

research Scalp Hypothermia as a Preventative Measure for Chemotherapy-Induced Alopecia: A Review of Controlled Clinical Trials

research Presentation, Impact and Prevention of Chemotherapy-Induced Hair Loss: Scalp Cooling Potentials and Limitations

research Hair Disorders in Patients with Cancer

research A Clinical and Biological Guide for Understanding Chemotherapy-Induced Alopecia and Its Prevention