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Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

The conclusion is that accurately replicating the complexity of the extracellular matrix in the lab is crucial for creating realistic human tissue models.

Plasmalogens activate a channel in cells that may stimulate hair growth.

Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.

Allopregnanolone changes gene expression in glioblastoma cells.

Alk1 in specific cells is crucial for proper nerve branching and hair function.

Deleting the PTEN gene in mice causes nerve cells to grow larger and heal better after injury, but may cause overgrowth and hair loss in older mice.

A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Bioengineering can potentially treat hair loss by regenerating hair follicles and cloning hair, but the process is complex and needs more research.

Methylated flavonoids may effectively reduce depression and inflammation caused by finasteride.

Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

The secretome from mesenchymal stromal cells shows promise for improving facial nerve injury treatment.

The document concludes that understanding adult stem cells and their environments can help improve skin regeneration in the future.

Improved understanding of stem cell mechanisms can enhance skin tissue engineering.

Epidermal stem cells show promise for treating orthopedic injuries and diseases.

Sweat gland development involves two unique skin cell programs and a temporary skin environment.

Signals from skin cells controlled by Rac proteins help turn certain precursor cells into white fat cells.

The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.

Lymphatic vessels are essential for health and can be targeted to treat various diseases.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Cells from the lower part of hair follicles are a promising, less invasive option for immune system therapies.

Mesenchymal stem cells show promise for treating various skin conditions and may help regenerate hair.

Tiny particles called extracellular vesicles show promise for treating skin conditions and promoting hair growth.

Nerve growth factor helps improve healing time and scar quality in burn wounds.

Exosomes could be a promising way to help repair skin and treat skin disorders.

The conclusion is that new plant-based treatments for hair loss may work by targeting certain enzymes.

Skin organoids from stem cells could better mimic real skin but face challenges.