January 2025 in “International Journal of Nanomedicine” In this study, a metformin-loaded rosemary-based nanoemulgel was found to significantly enhance hair follicle growth in rats, suggesting its potential as a new treatment for androgenetic alopecia due to its promising physicochemical properties and controlled drug release.
This study reported a significant upregulation of VEGF, which may help explain the beneficial effects of Ro on wound healing and hair loss, although further in-vitro and in-vivo studies are needed to better understand its molecular mechanisms and potential applications for skin disorders.
7 citations
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March 2023 in “Antioxidants” This study confirmed the antioxidant role of rosemary, suggesting its potential use in treating inflammatory and infectious skin conditions, but emphasizes that more large-scale controlled trials are necessary to fully understand its clinical impact.
This study found that rosemary oil significantly increased enzyme activities and IGF-1 mRNA expression related to hair growth in the skin of C57BL/6 mice.
2 citations
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January 2016 in “Journal of in silico & in vitro pharmacology” This study found that coencapsulating Minoxidil and Rosemary essential oil in liposomes increased Minoxidil's encapsulation efficacy, while Rosemary oil's entrapment was not significantly affected.
October 2025 in “Journal of Advanced Trends in Medical Research” This review highlights the potential of rosemary as a treatment for various types of alopecia, with effects possibly comparable to minoxidil and a favorable safety profile, though further large-scale studies are necessary to confirm these findings.
1 citations
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May 2022 in “Scientific African” In this study, oleogels containing rosemary oil significantly enhanced hair growth in albino rats, showing similar effects to 2% minoxidil after six weeks.
1 citations
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March 2023 in “PubMed” In this research, a 1% rosemary extract hair lotion was found to promote hair growth in mice more effectively than a standard minoxidil treatment.
August 2025 in “Processes” In this study, researchers used a network pharmacology approach to highlight significant interactions between compounds in rosemary (Salvia rosmarinus) and genes related to functional dyspepsia, suggesting potential pathways for developing treatments against gastrointestinal diseases.
1 citations
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June 2010 in “Daehan miyong hakoeji” Rosemary oil promotes hair growth.
November 2025 in “Revista Multidisciplinar do Nordeste Mineiro” This study found that rosemary essential oil may help stimulate hair growth and improve hair density with effects similar to traditional treatments but fewer side effects, though more clinical trials are needed.
September 2026 in “AJARCDE (Asian Journal of Applied Research for Community Development and Empowerment)” This study found that rosemary extract hair tonic, particularly at a 15% concentration, promoted greater hair growth in rats compared to 2% minoxidil, without any observed skin irritation.
4 citations
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July 2022 in “International Journal of Health Sciences” This review discusses rosemary's potential health benefits, including improved scalp circulation and skin protection, but reports no new clinical findings and highlights the need for better regulation and safety data on herbal medicines.
49 citations
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April 2012 in “Phytotherapy Research” This study found that topical Rosmarinus officinalis leaf extract improved hair regrowth in mice and inhibited androgen-associated mechanisms involved in hair loss.
August 2025 in “Journal of Drug Delivery Science and Technology” Combining minoxidil and rosemary oil in a gel promotes better hair growth than using them separately.
This study found that rosemary essential oil can be incorporated into an aromatherapy massage cream, with different oil and water ratios affecting its physical properties.
November 2015 in “Hair transplant forum international” This abstract discusses a randomized trial comparing rosemary oil and minoxidil 2% for treating androgenetic alopecia, but it reports no new clinical results; the authors mention ongoing research.
August 2023 in “The Indonesian Biomedical Journal” This study on UVB-exposed mice found that topical application of 10% Rosmarinus officinalis essential oil significantly increased hair length and follicle diameter, attributed potentially to its antioxidant compounds.
January 2010 in “Jounal of The Korean Society of cosmetology” Rosemary oil may promote hair growth by enhancing enzyme activities and IGF-1 expression.
This study found that 3% rosemary oil effectively stimulated hair growth in C57BL/6 mice, with results comparable to 3% minoxidil, showing faster regrowth and increased hair follicle number and depth.
This study found that the FER/MLO signaling module plays a crucial role in calcium oscillations and ROS production in root hair tip growth, with the MLO15 protein regulating these processes and restoring disrupted growth and signaling in fer mutant root hairs.
This review highlights that certain plant species, like Glycyrrhiza inflata and rosemary, show potential in treating skin diseases such as rosacea and alopecia, but emphasizes the need for more clinical studies to validate these findings.
November 2025 in “Current Cosmetic Science” This study reviews the potential of rosemary for hair loss treatment, highlighting its beneficial bioactive compounds that may support healthier scalps and promote hair growth, though inconsistencies in formulations and lack of long-term safety data suggest more research is needed.
January 2025 in “Turkish Journal of Trauma and Emergency Surgery” This study found that administering Rosmarinus Officinalis extract peritoneally shortly after surgery may raise the risk of evisceration at the abdominal incision site.
1 citations
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February 2024 in “Peer Review” This study reviewed the use of rosemary essential oil combined with photobiomodulation for treating androgenetic alopecia, highlighting the potential benefits of rosemary's antioxidant and vasodilatory properties alongside enhanced cellular processes from photobiomodulation.
July 2025 in “New Phytologist” This study demonstrated that the FER/MLO signaling module regulates calcium dynamics and ROS accumulation in root hair growth, with the constitutively active MLO (faNTA) able to restore normal development and signaling in specific mutant genotypes, highlighting MLO15's role in root hair tip growth regulation.
July 2024 in “Quality in Sport” This review highlights rosemary oil's potential therapeutic and cosmetic uses due to its anti-inflammatory, antioxidant, antibacterial, antifungal, antiviral, and anticancer properties, though further research is necessary to fully understand its mechanisms and develop safe, effective applications.
March 2024 in “Journal of integral sciences” This review highlights the interest in rosemary oil as a natural remedy for hair growth, contrasting its bioactive components and antioxidant properties with minoxidil's vasodilating mechanism, but notes that comprehensive clinical comparisons of their long-term efficacy and safety are still lacking.
November 2025 in “Natural Product Communications” This review compiles evidence indicating that rosemary essential oil may enhance cognitive function, sleep quality, mood, and pain management in aromatherapy; however, it also notes potential allergic reactions, emphasizing caution in its use.
January 2026 in “Ife Journal of Science” In this computational study, the researchers observed that compounds in rosemary extract showed promising interactions with proteins involved in androgenic alopecia, suggesting potential for hair growth promotion and hair loss prevention, warranting further in vitro and in vivo validation.