2 citations
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January 2009 This article reviews the development of a topical hair growth agent using natural extracts and reports no new clinical results, emphasizing the need for further evaluation of its efficacy.
January 2020 in “대한미용학회지” This review discusses various natural substances used in scalp improvement cosmetics and reports their potential benefits, without providing new clinical results, and suggests more comprehensive studies are needed.
36 citations
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February 2017 in “BMC Complementary and Alternative Medicine” In this study, Geranium sibiricum L. extract promoted hair growth in vitro with human dermal papilla cells and in vivo in mice, outperforming minoxidil by proliferating cells and stimulating growth factor expression, suggesting its potential as a hair growth treatment.
1 citations
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July 2022 in “Han'gug sigpum yeong'yang gwahag hoeji/Journal of the Korean society of food science and nutrition” In this study, ELE was found to protect against oxidative stress-induced testosterone reduction in TM3 Leydig cells by increasing testosterone synthesis and decreasing its conversion.
December 2016 in “University of Birmingham Institutional Research Archive (University of Birmingham)” This study suggests that the adrenal gland may contribute to prostate cancer treatment resistance and indicates potential steroid production or dependency in ovarian cancer.
35 citations
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May 2022 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism” This review discusses the current understanding of androgen biosynthesis, mechanisms of action, and their roles in human biology, as well as related congenital and acquired disorders, but it reports no new research findings.
November 2024 in “International Journal of Cosmetic Science” This study demonstrated that several botanical extracts possess antioxidant properties, reducing oxidative stress and lipid oxidation in scalp treatments, with rosemary extract showing potential to improve scalp condition in a 4-week consumer trial.
48 citations
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May 2021 in “Molecules” The researchers found that plant extracts from Papaver rhoeas L., Clitoria ternatea L., and Carthamus tinctorius L. are effective natural cosmetic dyes, offering intense and stable colors without cytotoxicity.
This study found that low-temperature rendering of black beans, peony, and green tea extracts retains higher antioxidant properties and effectively supports scalp health by strengthening follicles and moisturizing the scalp.
May 2024 in “Jurnal Penelitian Farmasi dan Herbal” In this experimental study using male rabbits, researchers found that a 7.5% concentration of green tea leaf ethanol extract hair tonic was nearly as effective in promoting hair growth as the positive control, minoxidil, over a 21-day period.
49 citations
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April 2012 in “Phytotherapy Research” This study found that topical Rosmarinus officinalis leaf extract improved hair regrowth in mice and inhibited androgen-associated mechanisms involved in hair loss.
December 2025 in “Jurnal Farmasi Tinctura” This study found that a hair tonic containing 15% ethanol extract of cocoa leaves effectively stimulated hair growth in rabbits, outperforming minoxidil 2%, and was safe with no skin irritation observed.
11 citations
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April 2017 in “Scholar Science Journals - International Journal of Biomedical Research” The researchers reported that a hydroalcoholic extract of Hibiscus Rosa Sinensis flowers was more effective than glibenclamide in reducing blood sugar levels in alloxan-induced diabetic rabbits, and demonstrated superior antioxidative and lipid-lowering effects, suggesting potential as an alternative antidiabetic treatment.
October 2022 in “International journal of pharmaceutical sciences review and research” This study compared the antioxidant and antidiabetic activities of Hibiscus rosa-sinensis leaf extract and Eclipta alba bark extract, finding that Hibiscus rosa-sinensis exhibited greater antidiabetic activity, whereas Eclipta alba demonstrated stronger antioxidant activity.
January 2026 in “Indus journal of bioscience research.” In this study, Hibiscus rosa-sinensis extract was used to formulate and evaluate herbal cosmetic creams for their antioxidant properties, stability, and effectiveness. The formulations demonstrated strong antioxidant potential, stability under various conditions, and favorable cosmetic qualities, suggesting HRS as a beneficial ingredient in skincare products.
July 2026 in “Journal of Medicinal Plants Studies” In this study, methanolic extracts of Hibiscus rosa-sinensis showed higher phenolic and flavonoid content, as well as greater concentrations of gallic acid and quercetin, than aqueous extracts, despite the latter yielding more extract, highlighting the effectiveness of methanol for extracting bioactive phytochemicals.
3 citations
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August 2024 in “Cosmetics” This study found that a 12-week regimen of a botanical supplement significantly improved skin and scalp health in women exposed to high pollution, enhancing factors like skin radiance, moisturization, and reducing wrinkle depth and scalp redness compared to a placebo.
51 citations
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May 2011 in “Phytotherapy Research” This study suggests that red ginseng rhizome extracts, particularly ginsenoside Ro, may promote hair re-growth in an androgenetic alopecia model due to their inhibitory activity on testosterone 5α-reductase.
5 citations
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January 2018 in “Thai Journal of Pharmaceutical Sciences (TJPS)” This study found that extracts from riceberry broken rice and crude riceberry rice oil contain bioactive compounds with antioxidant and tyrosinase-stimulating activities, suggesting potential use in hair product development.
November 2025 in “Discover Food” This study found that a catechins-rich Assam tea extract demonstrated antioxidant effects and hair growth promotion in mice, suggesting its potential as a natural alternative for treating hair loss.
April 2023 in “Journal of Investigative Dermatology” This report details the development of a PSR™ Terminalia extract with antioxidant and anti-aging potential, highlighting its rich composition in phenolic acids, polysaccharides, and organic acids, without new clinical results.
May 2026 in “Jurnal Riset Kefarmasian Indonesia” This study measured caffeine content in ethanolic extracts of robusta coffee beans, finding 221.58 mg of caffeine per gram of extract, which aligns with known levels for Coffea canephora.
September 2026 in “AJARCDE (Asian Journal of Applied Research for Community Development and Empowerment)” This study found that rosemary extract hair tonic, particularly at a 15% concentration, promoted greater hair growth in rats compared to 2% minoxidil, without any observed skin irritation.
32 citations
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February 2020 in “PTR. Phytotherapy research/Phytotherapy research” This review examines studies on rosemary extracts for immune function, noting promising in vitro and animal evidence but highlighting a lack of human data.
This study suggests that ethyl acetate extract of Equisetum debile may be effective for functional food and nutraceutical use due to its strong 5α-reductase, IL-6 inhibition, and lipid peroxidation activities without cytotoxic effects.
11 citations
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January 2016 in “Evidence-based Complementary and Alternative Medicine” This study found that rice bran ash extract and orthosilicic acid both increased melanin synthesis and related protein expression in melanocytes, suggesting potential therapeutic use for melanin deficiency.
23 citations
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January 2017 in “Journal of Oleo Science” This review discusses the use of supercritical carbon dioxide for extracting rice bran oil, noting its advantages over conventional methods for preserving nutrients and antioxidants, but provides no new experimental results.
8 citations
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February 2022 in “Molecules” This study found that Asparagus racemosus root extract significantly reduced facial sebum production and pore size in male volunteers, suggesting potential application as an anti-sebum ingredient in cosmetics.
4 citations
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May 2021 in “Research Journal of Science and Technology” This review discusses the therapeutic applications of Hibiscus rosa sinensis and reports no new clinical results; the authors highlight its potential in herbal medicine.
July 2023 in “International journal of research publications” In this study, topical application of 45% robusta green coffee bean extract in male wistar rats did not significantly enhance hair growth but effectively inhibited the increase of 5α-reductase type 1 levels when exposed to testosterone.