May 2023 in “International journal of molecular sciences” The ABCA4 gene protects hair follicle stem cells from toxic vitamin A byproducts.
March 2023 in “Biomedicine & Pharmacotherapy” GPR40 agonists help hair growth through the protein ANGPTL4.
January 2023 in “Theranostics” Mechanical force is important for the first contact between skin cells and hair growth in mini-organs.
49 citations,
November 2014 in “Journal of Medicinal Food” Red Ginseng Extract may help human hair grow by activating growth pathways and blocking negative effects of certain hormones.
20 citations,
June 2014 in “BMC genomics” Poplar seed hairs grow from the placenta at the ovary base, with endoreduplication playing a key role in their development, and share similar cellulose synthesis processes with cotton fibers.
8 citations,
November 2020 in “Nature Communications” Adult stem cells with Tp63 can form hair and skin cells when placed in new skin, showing they have hidden abilities for skin repair.
6 citations,
November 2018 in “Histochemistry and Cell Biology” Mongolian gerbils heal wounds differently than mice, with unique protein levels and gene expression that affect skin repair.
May 2024 in “Scientific reports” Twist2 is essential for scarless skin healing and hair growth in mouse fetuses.
36 citations,
March 2002 in “Journal of Biological Chemistry” Food deprivation increases MST enzyme in the brain, possibly affecting energy balance.
2 citations,
November 2013 in “International Journal of Dermatology” ALDOA levels drop in hair cells during hair loss.
April 2019 in “Advances in integrative medicine” HST and HST/F promote hair growth and may help treat alopecia.
218 citations,
October 2013 in “Proceedings of the National Academy of Sciences of the United States of America” Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.
116 citations,
August 2010 in “Nature” Scientists turned rat thymus cells into stem cells that can help repair skin and hair.
50 citations,
January 2016 in “The Journal of Clinical Endocrinology and Metabolism” Certain microRNAs in the fluid around eggs are linked to Polycystic Ovary Syndrome and may help diagnose it.
25 citations,
September 2018 in “Scientific Reports” Morroniside may help hair grow and stay in its growth phase by affecting certain cell signals.
16 citations,
September 2016 in “Neuropharmacology” Activating TSPO helps protect the retina from damage caused by high eye pressure in glaucoma.
383 citations,
February 2011 in “Nature Reviews Genetics” DNA profiling in forensics has improved, but predicting physical traits and ancestry from DNA has limitations and requires ethical consideration.
155 citations,
May 2016 in “Nature communications” Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.
87 citations,
April 2018 in “Biochemical and Biophysical Research Communications” Exosomes from dermal papilla cells can help grow hair and might treat hair loss.
80 citations,
April 2011 in “Plant physiology” White lupin uses specific genes to grow root hairs and access phosphorus when it's scarce.
68 citations,
March 2018 in “Biomaterials” Tiny needles with valproic acid can effectively regrow hair.
66 citations,
December 2013 in “Nature Cell Biology” Inactive hair follicle stem cells help prevent skin cancer.
35 citations,
August 2010 in “The American journal of pathology” Researchers created a new mouse model for studying Citrullinemia Type I and similar conditions, showing symptoms and treatment responses like those in humans.
32 citations,
April 2014 in “The journal of investigative dermatology/Journal of investigative dermatology” Loss of keratin K2 causes skin problems and inflammation.
29 citations,
April 2020 in “Journal of Tissue Engineering and Regenerative Medicine” The experiment showed that human skin grown in the lab started to form early hair structures when special cell clusters were added.
12 citations,
March 2011 in “Journal of pathology” Oncogenic K-ras causes rapid cancerous changes in the mouth's lining.
3 citations,
May 2018 in “Biochemical and Biophysical Research Communications” iNOS contributes to hair loss in obese diabetic mice and blocking it may encourage hair growth.
January 2014 in “Journal of Investigative Dermatology” Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.
January 2022 in “Biomedical Reports” Inaudible sound at 30 kHz can boost hair growth and decrease hair loss by promoting cell growth and reducing cell death in hair follicles.
7 citations,
March 2021 in “Molecular Medicine Reports” A mix of specific inhibitors and a growth factor helps keep hair growth cells from losing their properties in the lab.