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Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Melatonin receptors, found in many body parts, can help treat various diseases like depression and diabetes due to their effects on inflammation, tumor progression, sleep disorders, and body mass regulation.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

Altered retinoid metabolism in cicatricial alopecia suggests a balanced vitamin A diet may prevent the condition.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Hydroxypinacolone retinoate is a potent anti-aging ingredient for skin that is more effective and less irritating than other forms of retinoids.

PGD2 increases androgen receptor activity in hair cells, which could be targeted to treat hair loss.

The synthetic retinoid EC23 thickens skin and promotes hair growth more effectively and with a lower dose than natural retinoids.

As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.

DGAT1 enzyme is crucial for healthy skin and hair by regulating retinoid levels.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Removing vitamin D and calcium receptors in mice skin cells slows down skin wound healing.

Lithocholic acid helps hair growth and regeneration in alopecia by activating vitamin D receptors.

Five preservatives may disrupt hormone function and need more health and environmental risk assessment.

DHEA affects various tissues by interacting with multiple receptors and can be converted into sex hormones.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

Women generally handle heart enlargement better than men, but it's riskier for them if it occurs; hormones like estrogen offer some protection.

Hair loss from genetics and hormones can be treated with drugs or surgery.

Genetic variations affect dutasteride treatment response for male pattern hair loss.

Thyroid disease can cause hair loss and treating thyroid problems might help with hair disorders.

Thyroid hormone affects skin health, with too little causing rough, pale skin and too much leading to smooth, thin skin, and may also impact wound healing and skin conditions.

STAT3 signaling is important for healthy skin and hair follicles, and its disruption can lead to skin conditions like atopic dermatitis.

Male pattern baldness is often genetic and linked to a hormone, with treatments like finasteride and minoxidil being effective for some men.

Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.