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Acitretin is effective for severe skin conditions but has significant side effects and requires careful monitoring.

Feather patterns form through genetic and epigenetic controls, with cells self-organizing into periodic patterns.

Metabolic signals and cell shape influence how cells develop and change.

Platelet-rich plasma, which carries growth factors, could be a promising treatment for non-scarring hair loss, promoting hair growth and density with no major side effects.

Certain mouse strains develop a skin condition similar to a human hair loss disease due to genetic defects.

Nanomaterials show promise in improving wound healing but require more research on their potential toxicity.

The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.

Reducing Tyrosinase prevents mature color pigment cells from forming in mouse hair.

3D imaging shows clearer details of skin structure changes with age.

CXXC5 is a protein that controls cell growth and healing processes, and changes in its activity can lead to diseases like cancer and hair loss.

VDR regulation varies by tissue and is crucial for its biological functions.

Hair follicle stem cells can become different cell types and may help treat neurodegenerative disorders.

Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.

Hair growth and health are influenced by factors like age, environment, and nutrition, and are controlled by various molecular pathways. Red light can promote hair growth, and understanding these processes can help treat hair-related diseases.

RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

High-dose vitamin A and E with zinc improved blood sugar control and insulin function in diabetics, but may cause hair loss.

Thymic mesenchymal cells have unique gene expression that supports their specific functions in the thymus.

Combination therapies for androgenetic alopecia work best but can have significant side effects and costs.

Mesenchymal stem cells may help treat hair loss by improving hair cell growth and reducing inflammation.

Plant-based products can improve hair and skin health without harmful side effects.

Collagen and TGF-β2 help maintain hair cell shape and youthfulness.

Self-amplifying RNA could be a better option for protein replacement therapy with lower doses and lasting effects, but delivering it into cells is still challenging.

B6.Cg-Tyr c−2J Hr hr /J mice have a stronger delayed sunburn reaction and are good for UV research.

Caspases are enzymes important for both cell death and various non-lethal cell functions, affecting head development and hair growth, with different caspases playing specific roles.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

Cells from the lower part of hair follicles are a promising, less invasive option for immune system therapies.

Higher doses of isotretinoin may lead to more hair loss.

Hair follicles could be used to noninvasively monitor our body's internal clock and help identify risks for related diseases.

Thymic stromal lymphopoietin (TSLP) promotes hair growth, especially after skin injury.

Low dose cyclical nutrition therapy can consistently and safely improve hair growth and density without needing anti-androgens.