Combined Effect of High-Dose Vitamin A, Vitamin E Supplementation, and Zinc on Adult Patients with Diabetes: A Randomized Trial

    June 2020 in “ Journal of Advanced Research ”
    Eman Said, Shrook Mousa, May Fawzi, Nirmeen A. Sabry, Samar Farid
    TLDR High-dose vitamin A and E with zinc improved blood sugar control and insulin function in diabetics, but may cause hair loss.
    The randomized trial involving 98 adult patients with type 2 diabetes mellitus (T2DM) investigated the effects of high-dose vitamin A and E supplementation, with and without zinc, over 3 months. Participants were divided into three groups: control, vitamin A plus E, and vitamin A plus E with zinc. The group receiving vitamin A, E, and zinc showed significant improvements in fasting blood glucose, 2-hour postprandial blood glucose, glycated hemoglobin (HbA1c), fasting insulin, and β-cell function compared to the other groups. Two cases of hair loss were reported, indicating potential chronic toxicity. The study concluded that high-dose vitamin A and E, especially when combined with zinc, could enhance glycemic control and β-cell function in T2DM patients, though further research is needed to optimize dosing and minimize adverse effects.
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      community I feel like people here shrug off nutritional issues too quickly. Particularly for Retrograde Alopecia.

      in Chat  9 upvotes 1 year ago
      The user believes Retrograde Alopecia may be linked to vitamin imbalances, specifically from taking too much Vitamin E, A, Zinc, and Selenium, and suggests it could be a middle ground between Androgenic Alopecia and Telogen Effluvium. Treatments for hair loss mentioned include Androgen inhibitors and improving lifestyle factors like nutrition and sleep, with topical melatonin also recommended for Retrograde Alopecia.

      community We don't talk about vitamin E enough

       60 upvotes 5 years ago
      A user shared that taking vitamin E, specifically tocotrienols, seemed to reduce their hair shedding, and they are also using finasteride, minoxidil, and derma rolling for hair loss. Another user cautioned against high doses of vitamin E due to potential health risks.

      community Is this enough to regrow my lions mane and if no what am I missing?

      in Chat  1 upvotes 6 months ago
      A user is trying to regrow hair using a natural approach without Minoxidil or finasteride, focusing on micro-needling, red light therapy, and various oils and serums. Other users suggest that medical treatments are more effective for male pattern baldness.

      community 4 months on 2.5 mg OM, no improvement

      in Minoxidil  6 upvotes 1 year ago
      After 4 months on oral minoxidil with no significant hair regrowth, a user is frustrated and considering alternative treatments since they can't take finasteride due to side effects. Suggestions include natural DHT blockers, lifestyle changes, and other hair care tips.

      community what are the best multivitamins for hairloss?

      in Finasteride/Dutasteride  53 upvotes 2 years ago
      The conversation discusses which vitamins to take alongside 0.5mg finasteride for hair loss, with suggestions including a multivitamin, iron, zinc, B12, vitamin D, Nutrafol, collagen, vitamin C, saw palmetto, and magnesium. Nutrafol is noted for its benefits but also criticized for containing too much biotin.

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