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The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.

Polymeric nanoparticles show promise for treating skin diseases.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Hidradenitis suppurativa, a chronic skin disease, can be managed with antibiotics, lifestyle changes, and in severe cases, surgery. Early diagnosis and careful planning are key, and laser treatment can be an efficient solution for mild to severe cases.

Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Some medicinal plants can help heal wounds and may lead to new treatments.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Guidelines for diagnosing common hair loss include detailed history, clinical examination, and various diagnostic techniques.

Pregnancy can cause skin darkening, varicose veins, more sweating, hair growth, hair loss after birth, nail changes, and gum inflammation.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Tofacitinib may help treat severe hair loss, but more research is needed.

Flutamide rarely causes liver toxicity in prostate cancer patients.

Liposomes could improve how skin care products work but are costly and not very stable.

A specific drug can help treat Lichen Planopilaris, a condition causing permanent hair loss.