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This study found that using drug microplates in transdermal finasteride films enhances aqueous solubility and skin permeation compared to films with pure finasteride.

This study evaluated new aqueous gel formulations of minoxidil without irritants and found that the calcium alginate gel showed the best performance in terms of drug release and skin permeation.

This review explores nano-quercetin formulations to enhance the solubility, stability, and targeted delivery of quercetin, highlighting its potential efficacy in treating cancer, inflammation, metabolic diseases, and tissue regeneration, though challenges in biocompatibility, toxicity, and production remain, per this source.

This study concluded that fenugreek seed extract loaded solid lipid nanoparticles demonstrated enhanced skin retention and extended release, suggesting potential as a future alternative treatment for alopecia.

This study reports that a novel ketoconazole-loaded microneedle array significantly enhances drug delivery and retention in the skin, demonstrating improved hair growth in animal models, suggesting a promising treatment for androgenic alopecia that addresses current topical therapies' limitations.

In AGA animal models, this study found that finasteride-loaded microspheres provided rapid and sustained dihydrotestosterone suppression, promoting hair regrowth through dual-phase drug release.

This review discusses the integration of nanoparticles with microneedles to improve drug delivery through enhanced stability, bioavailability, and controlled release, noting ongoing challenges with stability, scalability, and safety.

The document describes how to tell different types of non-scarring hair loss apart by looking at hair and scalp tissue under a microscope.

This study found that the pH-sensitive hydrogel HECHA13, containing isoliquiritigenin, effectively inhibited the growth of Propionibacterium acnes and showed promise for transdermal delivery in acne treatment.

This article reviews the effects of various medications on male fertility, noting that while commonly used drugs can mostly have reversible impacts, conclusive human evidence remains limited.

This study found that testosterone and 5α-dihydrotestosterone induced apoptosis in dermal papilla cells from nonbalding scalp regions, suggesting a high androgen stimulus can trigger cell death related to androgenetic alopecia.

This review discusses hormonal influences on hair growth and suggests that understanding hormone-gene interactions may improve treatment of hirsutism and alopecia, but reports no new clinical findings.

This study found that grafting split-thickness human skin onto nude mice produces scars that mimic hypertrophic scar characteristics in humans, offering a useful model for studying scar formation and treatments.

This review examines the histopathologic features of four common types of noncicatricial alopecia and reports no new clinical results.

This article reviews the potential role of prolactin as a neuroendocrine modulator in skin biology and pathology, discussing its relevance for conditions such as psoriasis and hair growth, but reports no new clinical findings.

This study found that deleting Stim1 and Stim2 in mature T regulatory cells disrupts Ca 2+ signaling, preventing their differentiation and leading to severe autoimmune disorders in mice.

This study found that platelet-rich growth factor significantly reduced the release of proinflammatory cytokines in an in vitro rheumatoid arthritis model.

This study found that a testosterone patch and gel showed bioequivalent testosterone levels in hypogonadal men, but the patch mimicked a natural circadian profile, while the gel resulted in higher dihydrotestosterone levels.

This review discusses the potential of three-dimensional printed mesoporous scaffolds for drug delivery applications, particularly for bone cells and tissues, but reports no new clinical results.

In this study, a topical formulation with compounds from the monoterpenoid family significantly improved hair growth indicators like anagen:telogen ratio, hair fall, and visual hair density in men and women with pattern hair loss.

In this study, researchers reported that chronic UV exposure may contribute to androgenic alopecia progression by influencing hair cycle changes and exacerbating solar elastosis in the scalp.

This study reported that oleic acid-based nanovesicles improve follicular delivery and reduce side effects of minoxidil compared to traditional MXD lotions.

Human hair follicles have a unique metabolism that changes between growth stages and may contribute to baldness.

This study suggests that the hydrogel nanoparticle formulation of hair growth-promoting compounds may enhance hair follicle penetration and induce hair growth in tested models, demonstrating its potential as a hair growth treatment.

This study found that finasteride impaired stress reactivity and reduced exploratory and impulsive behaviors in rats, potentially by altering the hypothalamus-pituitary-adrenal axis function.

This study examined the structural and biochemical mechanisms of human lipocalin prostaglandin D synthase, detailing substrate and product binding processes at the catalytic site and suggesting potential for drug delivery targeting hydrophobic molecules.

This review examines the recent progress in using bioactive molecules for skin regenerative medicine and reports no new clinical results; the authors suggest this method could become a promising strategy for in situ skin regeneration.

This study found that gelatin microspheres loaded with platelet-rich plasma enhanced wound healing in rats by improving inflammatory and angiogenic responses compared to untreated wounds or PRP alone.

This study found that surface-modified liquid crystalline nanoparticles significantly enhanced skin permeation of finasteride and dutasteride compared to unmodified nanoparticles, suggesting potential for improved treatment efficacy in androgenetic alopecia.

This review discusses the concept of drug repositioning and highlights fragmin and protamine as emerging biomaterials for tissue engineering and regenerative medicine, but it reports no new clinical results.