263 citations,
February 2011 in “Journal of Controlled Release” Medium-sized particles penetrate hair follicles better than smaller or larger ones, which could improve delivery of skin treatments.
256 citations,
October 2013 in “Proceedings of the National Academy of Sciences of the United States of America” Growing human skin cells in a 3D environment can stimulate new hair growth.
238 citations,
April 2013 in “Development” Fat cells help recruit healing cells and build skin structure during wound healing.
211 citations,
April 2013 in “Development” More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.
208 citations,
January 2013 in “Lab on a Chip” The Multi-Organ-Chip improves the growth and quality of skin and hair in the lab, potentially replacing animal testing.
205 citations,
April 2005 in “Journal of Investigative Dermatology” Scientists have found a way to create hair follicles from skin cells of newborn mice, which can grow and cycle naturally when injected into adult mouse skin.
184 citations,
December 2018 in “Nature Communications” Researchers created human hair follicles using a new method that could help treat hair loss.
178 citations,
February 2018 in “Advances in wound care” New effective scar treatments are urgently needed due to the current options' limited success.
164 citations,
January 2014 in “Journal of Cutaneous and Aesthetic Surgery” PRP injections increase hair density and satisfaction in androgenetic alopecia patients.
135 citations,
January 2014 in “Seminars in Cell & Developmental Biology” Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.
134 citations,
January 2010 in “Biomedical research” Low oxygen conditions increase the hair-growing effects of substances from fat-derived stem cells by boosting growth factor release.
124 citations,
June 2020 in “Cell Stem Cell” Fat cells in the skin help start healing and form important repair cells after injury.
123 citations,
November 2012 in “Stem cells” MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.
122 citations,
April 2011 in “European Journal of Pharmaceutics and Biopharmaceutics” Particles around 100 nm can penetrate and stay in hair follicles without passing through healthy skin, making them safe for use in topical products and useful for targeted drug delivery.
113 citations,
November 2017 in “Scientific Reports” Tiny particles from stem cells help activate hair growth cells and encourage hair growth in mice without being toxic.
101 citations,
December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Scientists turned mouse stem cells into skin cells that can grow into skin layers and structures.
99 citations,
January 2014 in “Nature communications” Scientists created stem cells that can grow hair and skin.
96 citations,
June 2017 in “Nature Communications” A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.
93 citations,
February 2019 in “Carbohydrate Polymers” New nanocomposites with copper show promise for healing burn wounds and regenerating skin.
92 citations,
November 2015 in “Journal of Lipid Research” Skin fat helps with body temperature control and has other active roles in health.
84 citations,
January 2018 in “Biomaterials Science” Sericin hydrogels heal skin wounds well, regrowing hair and glands with less scarring.
84 citations,
June 2013 in “Stem Cells Translational Medicine” New methods for skin and nerve regeneration can improve healing and feeling after burns.
82 citations,
March 2016 in “Cell” The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.
78 citations,
January 2013 in “Biomaterials” Larger spheroids improve hair growth, but size doesn't guarantee thicker hair.
77 citations,
August 2020 in “Cell” Muscles and nerves that cause goosebumps also help control hair growth.
72 citations,
December 1996 in “Journal of Investigative Dermatology” Human hair follicles can regenerate after removal, but with low success rate.
72 citations,
December 2012 in “Journal of Investigative Dermatology” Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.
71 citations,
September 2006 in “Cell Transplantation” Fetal skin cells from a cell bank heal wounds faster and with less scarring than adult cells.
68 citations,
August 2014 in “Stem Cells Translational Medicine” Dermal papilla cells help wounds heal better and can potentially grow new hair.
64 citations,
August 2007 in “Artificial Organs” PHBV nanofiber matrices help wounds heal faster when used with hair follicle cells.