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Deleting the p63 gene in certain cells causes problems in thymus development and severe hair loss in mice.

Researchers found that hair follicle stem cells can become squamous cell carcinoma due to Ras activation, which could lead to new treatments.

Monotreme hair structure and protein distribution are similar to other mammals, but their inner root sheath cornifies differently, suggesting a unique evolution from reptile skin.

CREB, a protein that can promote cancer traits, is controlled by β-catenin in skin cancer cells.

LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

Reducing Tyrosinase prevents mature color pigment cells from forming in mouse hair.

Epigenetic mechanisms control skin development by regulating gene expression.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

People with alopecia areata have higher levels of RBP4 protein and antibodies against it.

Hair loss in three Southeast Asian women with kidney failure may be linked to their anemia treatment with erythropoietin.

FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.

Human hair keratins K85 and K35 create unique filament patterns important for early hair formation.

Minoxidil breakdown varies by enzymes, affecting hair loss treatment effectiveness.

Erythropoietin helps hair grow and could be a potential treatment for hair loss.

Altered retinoid metabolism in cicatricial alopecia suggests a balanced vitamin A diet may prevent the condition.

Phototrichogram helps assess hair loss severity.

The document concludes that understanding sulfation biology is crucial for creating treatments due to its importance in biological functions and disease.

The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.

Certain existing drugs, like glycopyrronium and botulinum toxin type A, may help treat excessive sweating.

S100A3 protein is crucial for hair shaft formation in mice.

The C3H/HeJ mouse model is useful for studying and testing treatments for alopecia areata.

People with atopic dermatitis have more CD4+ T cells that respond to a certain bacterial lipid, which may play a role in the skin condition's inflammation.

COVID-19 and hypopituitarism (reduced pituitary gland function) are linked, with the latter's related health issues potentially worsening COVID-19 outcomes, and COVID-19 possibly increasing risk for pituitary complications.

Lifestyle changes are the first step in treating infertility in PCOS, followed by medications like clomiphene and metformin, and then surgery if needed.

A cancer patient died from a severe skin reaction after taking the drug cetuximab.

Certain drugs that block specific enzymes can help treat prostate diseases.

A substance called Vascular Endothelial Growth Factor can protect certain hair follicle stem cells from damage caused by androgens, suggesting a new possible treatment for hair loss.

The document concludes that various drugs for men's health issues are in development, with treatments for sexual dysfunction and prostate conditions being the most advanced.