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Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

A new protein was made to detect specific skin cell growth receptors and worked in normal skin but not in skin cancer cells.

A compound named ZCZ90 can increase muscle spindle firing, potentially helping treat muscle spasms and hypertension.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

Finasteride may improve prostate cancer treatment outcomes.

Dutasteride and finasteride affect different cell types differently.

Mutations in the Vitamin D receptor gene can cause hair loss similar to mutations in the Hairless gene.

Mutations in the vitamin D receptor cause hereditary vitamin D-resistant rickets, leading to poor bone health and requiring high calcium doses for treatment.

New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.

New compounds may soon be tested to treat excessive hair growth in women.

Tirzepatide might help manage PCOS in obese patients but needs more research to confirm safety and effectiveness.

Bicalutamide may help treat female pattern hair loss.

Two rare genetic diseases cause severe rickets in children due to defects in vitamin D metabolism.

Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.

Finasteride and flutamide effectively reduce hirsutism in PCOS women, with flutamide also lowering hormone levels.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.

Progestogens are essential in menopausal hormone therapy to prevent uterine cancer and must be chosen carefully based on individual needs.

Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.

A child with rickets and hair loss might have a rare type of rickets that doesn't improve much with usual vitamin D and calcium treatment.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Minoxidil treats high blood pressure and side effects can be managed.

A boy with severe Vitamin D-resistant rickets did not respond to treatment and lacked a common symptom, suggesting a need for alternative treatments.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Targeted cancer therapies have a significant but lower risk of causing hair loss compared to chemotherapy.

Intermittent low-dose finasteride works as well as daily use for treating excessive hair growth in women.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.