Search

for
Search:

GlossaryAryl Hydrocarbon Receptor

protein that binds environmental toxins, affecting gene expression

The Aryl Hydrocarbon Receptor (AhR) is a protein within cells that binds to various environmental toxins, such as dioxins, and activates the expression of certain genes. This receptor plays a crucial role in how the body responds to these toxins, influencing processes like detoxification, immune response, and even skin and hair health.

Related Terms

Learn

0 / 0 results

— no results

Research

5 / 339 results

research Activated Wound Phenotype and Microbial Dysbiosis Driven by AhR Suppression in Hidradenitis Suppurativa Tunnels

July 2025 in “Journal of Investigative Dermatology”

Reduced AhR signaling in HS tunnels leads to persistent inflammation and microbial imbalance.

research Cicatricial Alopecia Symposium 2011: Lipids, Inflammation, and Stem Cells

4 citations , May 2012 in “Journal of Investigative Dermatology”

The symposium concluded that a specific lipid might cause hair loss, inflammation is a key factor, and stem cells in bald scalps aren't working right, suggesting new treatment targets.

Inhibition of Cholesterol Biosynthesis Modulates Epithelial-Mesenchymal Transition in Primary Cicatricial Alopecia Through TGFβ and Angiotensin Receptors

research Inhibition of Cholesterol Biosynthesis Modulates Epithelial-Mesenchymal Transition in Primary Cicatricial Alopecia Through TGFβ and Angiotensin Receptors

May 2023 in “Journal of Endocrinology and Reproduction”

Blocking cholesterol production may help control hair loss in Primary Cicatricial Alopecia by affecting key regulators.

research Aryl Hydrocarbon Receptor Overexpression in Miniaturized Follicles in Female Pattern Hair Loss

4 citations , June 2017 in “Anais Brasileiros De Dermatologia”

Aryl hydrocarbon receptor overexpression found in miniaturized hair follicles in female hair loss.

2,3,7,8-Tetrachlorodibenzo-p-dioxin Increases the Expression of Genes in the Human Epidermal Differentiation Complex and Accelerates Epidermal Barrier Formation

research 2,3,7,8-Tetrachlorodibenzo-p-dioxin Increases the Expression of Genes in the Human Epidermal Differentiation Complex and Accelerates Epidermal Barrier Formation

86 citations , August 2011 in “Toxicological sciences”

TCDD speeds up skin barrier formation by increasing certain gene expressions.

View more "aryl hydrocarbon receptor" in research →

Community Join

4 / 4 results

community PP405 Identity Research

UmbrellaLabsResearch in Research 292 upvotes 6 months ago

PP405 is a potential hair loss treatment that inhibits mitochondrial pyruvate carriers, increasing lactate dehydrogenase activity and stimulating hair follicle stem cells. In a phase 1 trial, 31% of participants showed over 20% hair density increase with PP405 treatment.

community PP405 bandwagon, time to resume the hype train.

in Treatment 164 upvotes 6 months ago

PP405 shows promise in hair regrowth, potentially outperforming existing treatments like finasteride and minoxidil, with significant results in just four weeks. The treatment is still in early stages, with further trials needed to determine its long-term effectiveness and optimal dosage.

community Getting PP405. Now…. or as soon as possible

in Research/Science 146 upvotes 9 months ago

People are discussing obtaining and testing PP405 for hair loss treatment, with concerns about its purity and effectiveness. Some are considering delaying hair transplants, while others suggest using existing treatments like finasteride and minoxidil.

community PP405 is out for sale on everychem.

in Product 100 upvotes 7 months ago

PP405 is suspected to be a scam, with users doubting its legitimacy and effectiveness. Many recommend using proven treatments like finasteride and minoxidil.