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    Glossary Aryl Hydrocarbon Receptor

    protein that binds environmental toxins, affecting gene expression

    The Aryl Hydrocarbon Receptor (AhR) is a protein within cells that binds to various environmental toxins, such as dioxins, and activates the expression of certain genes. This receptor plays a crucial role in how the body responds to these toxins, influencing processes like detoxification, immune response, and even skin and hair health.

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    Research 30 of 334

    1. TCDD-induced activation of aryl hydrocarbon receptor regulates the skin stem cell population Medical hypotheses · 2015 · 9 citations
    2. Frontal Fibrosing Alopecia. An Example of Disrupted Aryl Hydrocarbon Receptor-Mediated Immunological Homeostasis in the Skin? Clinical, cosmetic and investigational dermatology · 2020 · 8 citations
    3. Aryl hydrocarbon receptor overexpression in miniaturized follicles in female pattern hair loss Anais Brasileiros De Dermatologia · 2017 · 4 citations
    4. Frontal Fibrosing Alopecia. An Example of Disrupted Aryl Hydrocarbon Receptor-Mediated Immunological Homeostasis in the Skin? DOAJ (DOAJ: Directory of Open Access Journals) · 2020
    5. Inhibition of Cholesterol Biosynthesis Modulates Epithelial-Mesenchymal Transition in Primary Cicatricial Alopecia Through TGFβ and Angiotensin Receptors Journal of Endocrinology and Reproduction · 2023
    6. Apoptose, microinflamação e expressão de receptores de hidrocarboneto arílico nos folículos pilosos de pacientes com alopecia de padrão feminino UNESP Institutional Repository (São Paulo State University) · 2013
    7. The impact of air pollution on skin and related disorders: A comprehensive review Dermatologic Therapy · 2021 · 98 citations
    8. 2,3,7,8-Tetrachlorodibenzo-p-dioxin Increases the Expression of Genes in the Human Epidermal Differentiation Complex and Accelerates Epidermal Barrier Formation Toxicological sciences · 2011 · 86 citations
    9. Environmental Air Pollutants Affecting Skin Functions with Systemic Implications International Journal of Molecular Sciences · 2023 · 70 citations
    10. Air Pollution and Skin Diseases Annals of Dermatology · 2025 · 23 citations
    11. Cicatricial Alopecia Symposium 2011: Lipids, Inflammation and Stem Cells Journal of Investigative Dermatology · 2012 · 4 citations
    12. The AhR pathway is dysregulated in alopecia areata Journal of Translational Autoimmunity · 2025 · 2 citations
    13. A Hero Revealed: Targeting the AHR for treatment of inflammatory skin diseases Radboud University Press eBooks · 2025
    14. 0877 Activated wound phenotype and microbial dysbiosis are driven by AhR suppression in hidradenitis suppurativa tunnels Journal of Investigative Dermatology · 2025
    15. 705 Particulate matter induces inflammatory response in human outer root sheath cells via oxidative stress-dependent MAPK and JAK-STAT signaling pathways 2022
    16. 072 Covid-19 and male androgenetic alopecia: Systematic investigation of a potential epidemiological and genetic association Journal of Investigative Dermatology · 2021
    17. Melatonin Receptors and Their Role in Human Diseases Springer eBooks · 2013 · 4 citations
    18. Air pollution and skin diseases: Adverse effects of airborne particulate matter on various skin diseases Life Sciences · 2016 · 295 citations
    19. Beyond acne: Current aspects of sebaceous gland biology and function Reviews in Endocrine and Metabolic Disorders · 2016 · 97 citations
    20. A new path in defining light parameters for hair growth: Discovery and modulation of photoreceptors in human hair follicle Lasers in surgery and medicine · 2017 · 70 citations
    21. Mechanisms of Puerariae Lobatae Radix in regulating sebaceous gland secretion: insights from network pharmacology and experimental validation Frontiers in Pharmacology · 2024 · 3 citations
    22. Precision therapeutics in non-scarring alopecia: a systemic genomic and pathway-based framework for targeted interventions ADMET & DMPK · 2025
    23. Expression and function of nuclear receptor co-activator 4: evidence of a potential role independent of co-activator activity Cellular and Molecular Life Sciences · 2012 · 26 citations
    24. 50285 Oxytocin receptor is present in keratinocytes near touch and pain sensory neurons Journal of the American Academy of Dermatology · 2024
    25. Triclocarban, Triclosan, Bromochlorophene, Chlorophene, and Climbazole Effects on Nuclear Receptors: An <i>in Silico</i> and <i>in Vitro</i> Study Environmental health perspectives · 2020 · 29 citations
    26. 078 The transmembrane protein LRIG1 regulates receptor tyrosine kinases in skin development and homeostasis Journal of Investigative Dermatology · 2017
    27. The Effects of Environmental Pollutants and Exposures on Hair Follicle Pathophysiology Skin appendage disorders · 2024
    28. Microarray analysis of androgenetic and senescent alopecia: Comparison of gene expression shows two distinct profiles Journal of Dermatological Science · 2013 · 27 citations
    29. Sebaceous immunobiology - skin homeostasis, pathophysiology, coordination of innate immunity and inflammatory response and disease associations Frontiers in immunology · 2022 · 21 citations
    30. Calcium regulation of stem cells EMBO reports · 2020 · 25 citations