Oxytocin Receptor Is Present in Keratinocytes Near Touch and Pain Sensory Neurons

    Nithisha Cheedalla, Victoria E. Abraira
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    TLDR Oxytocin receptors are found in skin cells near touch and pain neurons.
    The study investigates the presence and role of the oxytocin receptor (OxyR) in keratinocytes near touch and pain sensory neurons in the skin. Using mouse genetic tools, researchers confirmed OxyR expression in keratinocytes of hairy skin, particularly around hair follicles where touch sensory neurons are located. This suggests a potential relationship between OxyR, keratinocytes, and sensory neuron function. Future steps include assessing skin sensitivity in mice with activated OxyR in keratinocytes to better understand its role in skin conditions and potential for novel topical therapies for painful skin disorders.
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