Oxytocin Receptor Is Present in Keratinocytes Near Touch and Pain Sensory Neurons

September 2024 in “ Journal of the American Academy of Dermatology ”

Nithisha Cheedalla, Victoria E. Abraira

oxytocin receptor keratinocytes hair follicles sensory neurons hairy skin skin sensitivity topical therapies painful skin disorders OxyR skin cells hair roots nerve cells skin treatments painful skin conditions

TLDR Oxytocin receptors are found in skin cells near touch and pain neurons.

The study investigates the presence and role of the oxytocin receptor (OxyR) in keratinocytes near touch and pain sensory neurons in the skin. Using mouse genetic tools, researchers confirmed OxyR expression in keratinocytes of hairy skin, particularly around hair follicles where touch sensory neurons are located. This suggests a potential relationship between OxyR, keratinocytes, and sensory neuron function. Future steps include assessing skin sensitivity in mice with activated OxyR in keratinocytes to better understand its role in skin conditions and potential for novel topical therapies for painful skin disorders.

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Oxytocin Receptor Is Present in Keratinocytes Near Touch and Pain Sensory Neurons

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