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Phytotherapeutic compounds and supplements can help manage Polycystic Ovarian Syndrome (PCOS).

PCOS may increase the risk of certain cancers.

PCOS is linked to a higher risk of endometrial cancer but not ovarian or breast cancer, and more research is needed on its role in cancer development and treatment effects.

MicroRNAs could be key biomarkers and therapeutic targets for PCOS.

Natural products may help treat skin inflammation from abnormal adrenal hormones.

Changes in gut bacteria can contribute to the development of Polycystic Ovary Syndrome (PCOS), affecting metabolism, immunity, and causing inflammation. Treatments may involve adjusting these factors.

Acne treatment with isotretinoin increases the presence of p53, a protein, in skin and oil glands, which may help reduce acne severity.

Volatile organic compounds can cause inflammation and increase the risk of autoimmune diseases.

Pinus densiflora extract may help improve memory and reduce brain inflammation.

The new Exo/Gel dressing with stem cell-derived particles helps skin wounds heal faster.

Parthenolide promotes hair growth in mice and may influence pathways related to male pattern baldness.

Most hair follicle stem cells do not protect their DNA by dividing it unevenly.

Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.

Microneedle technology has improved drug delivery and patient comfort but needs more research for broader use.

Disrupting the Flcn gene in mice causes early kidney cysts and tumors, which can be treated with rapamycin.

Higher miR-34a levels and the A variant of the MIR-34A gene are linked to increased risk and severity of alopecia areata.

Lower lipin 1β in belly fat is linked to insulin resistance in people with polycystic ovary syndrome.

Spinach-derived thylakoid supplements plus a low-calorie diet helped obese women with polycystic ovary syndrome lose weight and improve their metabolism.

Isotretinoin improves severe acne without changing androgen or insulin levels but may increase body weight and triglycerides.

Apple polyphenols, especially from unripe apples, can help prevent cells from turning into fat cells.

Boosting mitochondrial energy production with supplements like acetyl-L-carnitine may improve aging-related cellular function and health conditions.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Women with PCOS have similar levels of certain proteins compared to women without PCOS, and these proteins don't independently cause PCOS.

Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.

SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

Obese women with PCOS show a male-like pattern in certain fat tissue gene expressions.