This systematic review and meta-analysis found that polyphenolic interventions significantly improved hair density and total area hair count in adults with non-scarring alopecia, but substantial heterogeneity was observed.
January 2026 in “British Journal of Dermatology” This study found that combined microneedling with minoxidil significantly improved hair count and diameter in patients with androgenetic alopecia compared to minoxidil alone, despite mild adverse events, and microneedling parameters like depth and duration did not significantly affect outcomes.
September 2025 in “Journal of the American Academy of Dermatology” Combining minoxidil and PRP is more effective for hair growth than using either alone.
July 2021 in “Medical journal, Armed Forces India” This study reported that using platelet-rich plasma as an intraoperative holding solution significantly improved hair density and follicular growth in hair restoration surgery for androgenetic alopecia.
In this study, mesotherapy containing nutritional supplements was found to increase patient satisfaction and improve the number of hair follicles more effectively than topical minoxidil in treating female pattern hair loss, though both methods showed similar overall efficacy in hair density and hair loss reduction.
The systematic review and meta-analysis evaluated the efficacy and safety of combining microneedling therapy with other treatments for androgenic alopecia. The analysis included multiple randomized clinical trials, providing a comprehensive assessment of the combined treatment approach. The findings suggested that microneedling, when used in conjunction with other therapies, improved hair growth outcomes in patients with androgenic alopecia. The study also reported that the combined treatment was generally safe, with no significant adverse effects noted. However, as the review was completed but not published, the detailed results and specific number of participants involved in the trials were not disclosed.
127 citations
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July 1996 in “Journal of The American Academy of Dermatology” This study found that in women undergoing chemotherapy after breast surgery, topical minoxidil significantly shortened the duration of hair loss compared to a placebo without significant side effects.
48 citations
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July 2009 in “The Journal of Sexual Medicine” In this study, 50 mg/day of DHEA supplementation in postmenopausal women did not significantly improve sexual function compared to a placebo over 26 weeks.
20 citations
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June 2020 in “Journal of Advanced Research” This study found that high-dose vitamin A and E supplementation with zinc may improve glycemic control and beta-cell function in patients with type 2 diabetes, compared to no supplements.
7 citations
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December 2020 in “Dermatologic Therapy” In this study, intradermal injections of 0.5% minoxidil significantly improved hair growth and volume in women with female androgenetic alopecia compared to a placebo, with a good safety profile reported.
4 citations
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December 2019 in “Trials” This study aims to evaluate the effectiveness of YH0618 granules in preventing chemotherapy-induced hair loss in breast cancer patients through a randomized, double-blind, multi-center clinical trial, focusing on potential mechanisms related to kidney deficiency as understood in Chinese Medicine. Results are not yet reported.
3 citations
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July 2019 in “Supportive Care in Cancer” The lotion CG428 did not show effectiveness in treating permanent hair loss in breast cancer survivors.
2 citations
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April 2024 in “Journal of Clinical Psychopharmacology” In this study, dutasteride 1 mg daily reduced heavy drinking days and drinks per week among treatment-seeking men, particularly benefiting those with high baseline drinking to cope motives.
June 2026 in “Lasers in Medical Science” This randomized trial found that diode laser achieved more favorable long-term hair removal outcomes but induced more discomfort and transient adverse effects compared to intense pulsed light in women with Fitzpatrick skin types I-IV.
February 2023 in “Journal of Cosmetic Dermatology” This study found that microneedling combined with either topical vitamin D3 or bimatoprost was more effective for hair regrowth in localized alopecia areata than microneedling alone, though differences between the two additives disappeared after three months.
219 citations
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March 2004 in “Journal of The American Academy of Dermatology” In this 48-week trial, 5% topical minoxidil was more effective than both 2% minoxidil and placebo in promoting hair growth in women with female pattern hair loss, with notable improvements in nonvellus hair count and hair growth assessments.
26 citations
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December 2019 in “Indian Journal of Dermatology, Venereology and Leprology” This study found that platelet-rich plasma combined with topical minoxidil was more effective in increasing hair density for male-type baldness than either treatment alone.
1 citations
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April 2024 in “Skin research and technology” This clinical trial found that topical rosuvastatin and melatonin creams significantly reduced the severity of mild to moderate plaque psoriasis over 12 weeks, with a satisfactory safety profile.
May 2026 in “International Journal of Drug Delivery Technology” This clinical trial found that using a 45-degree angled implanter with the bevel facing the skin in FUE hair transplantation significantly reduced insertion resistance, graft popping, and bleeding, while improving efficiency and graft alignment compared to conventional methods.
August 2025 in “International Journal of Ayurveda360” In this randomized controlled trial, the combination of Bhringaraja Taila Shiroabhyanga and Yastimadhuka Taila Nasya was found to significantly improve hair density, reduce hair fall, and decrease scalp visibility in females with Khalitya compared to Nasya alone, with no reported adverse effects.
January 2023 in “Dermatologic Therapy” In this randomized controlled trial, the nutritional supplement PPT5 α was associated with increased terminal hair percentages and improved self-assessed hair parameters in women with early-stage androgenetic alopecia.
June 2026 in “International Journal of Ayurvedic Medicine (Hyderabad)” This study found that Asthimajjapachak Churna provided significantly more therapeutic relief from hair fall than Shwadamshtradi Rasayana Churna in young females over 30 days.
June 2026 in “International Journal of Ayurvedic Medicine” The study found that Asthimajjapachak Churna led to greater improvement in managing hair fall among young females compared to Shwadamshtradi Rasayana Churna, particularly through alleviation of Asthigata dosha.
October 2019 in “International Journal of Research in Dermatology” This study found that combining topical minoxidil with oral spironolactone improved hair loss outcomes in women with female pattern hair loss when compared to minoxidil alone, but benefits plateaued after 6 months.
11 citations
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January 2019 in “International Journal of Trichology” This study observed no significant improvement of mesotherapy over 5% topical minoxidil for male androgenic alopecia, despite a small increase in hair shaft diameter variation with mesotherapy.
6 citations
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December 2024 in “BMC Women s Health” This study found that a lifestyle promotion program led to significant weight loss, waist reduction, and improved menstrual regularity and acne symptoms in adolescents with PCOS, while also promoting similar benefits in non-PCOS adolescents.
4 citations
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February 2025 in “Nutrients” This randomized controlled trial found that consuming *Gynostemma pentaphyllum* extract significantly improved hair elasticity, density, and diameter over 24 weeks without severe adverse events, suggesting it as a safe functional food ingredient for hair health improvement.
2 citations
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November 2025 in “Nutrition Journal” This study found that an 8-week supplementation with specific probiotic strains improved hormonal markers and oxidative stress while decreasing inflammation in women with PCOS, although clinical symptoms like acne and hirsutism showed no significant improvement compared to the placebo group.
2 citations
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February 2023 in “BMC endocrine disorders” This study found that curcumin lowered fasting blood sugar levels and improved menstruation characteristics in women with polycystic ovary syndrome, but it did not affect other metabolic, hormonal, or hirsutism indices.
1 citations
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January 2024 in “Dermatologic Therapy” This study found that both methotrexate and azathioprine were equally effective and well-tolerated in improving symptoms of lichen planopilaris over six months, with no significant difference between the two treatments in terms of efficacy.